ArticleGenetics1996
Is esterase-P encoded by a cryptic pseudogene in Drosophila melanogaster?
Article in Genetics, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 29 citations in OpenAlex.
- Adaptation and Cryptic Pseudogenization in Penguin Toll-Like Receptors.Molecular biology and evolution · 2022Article
- Birth and death of genes and functions in the beta-esterase cluster of Drosophila.Journal of molecular evolution · 2009Article
- Positive and negative selection in the beta-esterase gene cluster of the Drosophila melanogaster subgroup.Journal of molecular evolution · 2006Article
- Nucleotide variation in the tinman and bagpipe homeobox genes of Drosophila melanogaster.Genetics · 2004Article
- Nucleotide variation of the Est-6 gene region in natural populations of Drosophila melanogaster.Genetics · 2003Article
- Molecular population genetics of the beta-esterase gene cluster of Drosophila melanogaster.Journal of genetics · 2003Article
- Genomewide distribution of high-frequency, completely mismatching SNP haplotype pairs observed to be common across human populations.American journal of human genetics · 2003Article
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- Molecular evolution of the Cecropin multigene family in Drosophila. functional genes vs. pseudogenes.Genetics · 1998Article
- DNA variation at the Sod locus of Drosophila melanogaster: an unfolding story of natural selection.Proceedings of the National Academy of Sciences of the United States of America · 1997Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
We have amplified and sequenced the gene encoding Esterase-P (Est-P) in 10 strains of Drosophila melanogaster. Three premature termination codons occur in the coding region of the gene in two strains. This observation, together with other indirect evidence, leads us to propose that Est-P may be a pseudogene in D. melanogaster. Est-P would be a "cryptic" pseudogene, in the sense that it retains intact the coding sequence (without stop codons and other alterations usually observed in pseudogenes) in most D. melanogaster strains. We conjecture that the beta-esterase cluster may consist in other Drosophila species of functional and nonfunctional genes. We also conjecture that the rarity of detected pseudogenes in Drosophila may be due to the difficulty of discovering them, because most of them are cryptic.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.