ArticleProtein science : a publication of the Protein Society1996
Saccharomyces cerevisiae mitochondria lack a bacterial-type sec machinery.
Article in Protein science : a publication of the Protein Society, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Folding and Insertion of Transmembrane Helices at the ER.International journal of molecular sciences · 2021Review
- Vestiges of the Bacterial Signal Recognition Particle-Based Protein Targeting in Mitochondria.Molecular biology and evolution · 2021Article
- Cotranslational recruitment of ribosomes in protocells recreates a translocon-independent mechanism of proteorhodopsin biogenesis.iScience · 2021Article
- Genetic and Physical Interaction Studies Reveal Functional Similarities between ALBINO3 and ALBINO4 in Arabidopsis.Plant physiology · 2015Article
- A conserved cysteine residue of Bacillus subtilis SpoIIIJ is important for endospore development.PloS one · 2014Article
- The mitochondrial oxidase assembly protein1 (Oxa1) insertase forms a membrane pore in lipid bilayers.The Journal of biological chemistry · 2012Article
- Interaction studies between the chloroplast signal recognition particle subunit cpSRP43 and the full-length translocase Alb3 reveal a membrane-embedded binding region in Alb3 protein.The Journal of biological chemistry · 2011Article
- Roles of Oxa1-related inner-membrane translocases in assembly of respiratory chain complexes.Biochimica et biophysica acta · 2009Review
- Translocation of mitochondrially synthesized Cox2 domains from the matrix to the intermembrane space.Molecular and cellular biology · 2007Article
- Mba1, a membrane-associated ribosome receptor in mitochondria.The EMBO journal · 2006Article
- Streptococcal viability and diminished stress tolerance in mutants lacking the signal recognition particle pathway or YidC2.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
- YidC family members are involved in the membrane insertion, lateral integration, folding, and assembly of membrane proteins.The Journal of cell biology · 2004Review
- Escherichia coli YidC is a membrane insertase for Sec-independent proteins.The EMBO journal · 2004Article
- Structure and function of the chloroplast signal recognition particle.Current genetics · 2004Review
- The thylakoid membrane protein ALB3 associates with the cpSecY-translocase in Arabidopsis thaliana.The Biochemical journal · 2002Article
- Cox18p is required for export of the mitochondrially encoded Saccharomyces cerevisiae Cox2p C-tail and interacts with Pnt1p and Mss2p in the inner membrane.Molecular biology of the cell · 2002Article
- YidC, the Escherichia coli homologue of mitochondrial Oxa1p, is a component of the Sec translocase.The EMBO journal · 2000Article
- Mutations affecting a yeast mitochondrial inner membrane protein, pnt1p, block export of a mitochondrially synthesized fusion protein from the matrix.Molecular and cellular biology · 1999Article
- Molecular cloning of the maize gene crp1 reveals similarity between regulators of mitochondrial and chloroplast gene expression.The EMBO journal · 1999Article
- Oxa1p, an essential component of the N-tail protein export machinery in mitochondria.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The bacterial Sec genes encode a generalized protein export machinery. Although the mitochondria present in eukaryotic cells are derived from bacterial ancestors, a comprehensive search of the complete genomic sequence for the eukaryotic yeast Saccharomyces cerevisiae did not reveal any close homologs of the bacterial Sec genes, strongly suggesting that yeast mitochondria lack a generalized bacterial-type export system. This finding has implications for the sorting of imported mitochondrial proteins to the intermembrane space compartment, and also for the insertion of mitochondrially encoded proteins into the inner membrane.
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