ArticleGenetica1996
Clusters of identical new mutation in the evolutionary landscape.
Article in Genetica, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Non-Poissonian Bursts in the Arrival of Phenotypic Variation Can Strongly Affect the Dynamics of Adaptation.Molecular biology and evolution · 2024Article
- A perspective on the evolution of germ-cell development and germinal mosaics of deleterious mutations.Genetica · 2015Review
- Efficient Estimation of Mutation Rates during Individual Development by Minimization of Chi-Square.PloS one · 2015Article
- Pattern of mutation rates in the germline of Drosophila melanogaster males from a large-scale mutation screening experiment.G3 (Bethesda, Md.) · 2014Article
- Article
- Highly variable recessive lethal or nearly lethal mutation rates during germ-line development of male Drosophila melanogaster.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Adaptation of Drosophila melanogaster to increased NaCl concentration due to dominant beneficial mutations.Genetica · 2011Article
- Microsatellite evolution: Mutations, sequence variation, and homoplasy in the hypervariable avian microsatellite locus HrU10.BMC evolutionary biology · 2008Article
- Correlates of substitution rate variation in mammalian protein-coding sequences.BMC evolutionary biology · 2008Article
- Estimating mutation rate: how to count mutations?Genetics · 2003Article
- Spontaneous occurrence of a Robertsonian fusion involving chromosome 19 by single whole-arm reciprocal translocation (WART) in wild-derived house mice.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2000Article
- Article
- Rates of spontaneous mutation.Genetics · 1998Review
- Clusters of identical new mutations can account for the "overdispersed" molecular clock.Genetics · 1997Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In contrast to the common assumption that each new mutant results from a unique, independent mutation event, clusters of identical premeiotic mutant alleles are common. Clusters can produce large numbers of related individuals carrying identical copies of the same new genetic change. By entering the gene pool in multiple copies at one time, clusters can influence fundamental processes of population genetics. Here we report evidence that clusters can increase the arrival and fixation probabilities and can lengthen the average time to extinction of new mutations. We also suggest it may be necessary to reconsider other fundamental elements of population genetic theory.
Indexed as
Identifiers
8976063What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.