ArticleGenetica1996
Pegasus, a small terminal inverted repeat transposable element found in the white gene of Anopheles gambiae.
Article in Genetica, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 26 citations in OpenAlex.
- Birth of three stowaway-like MITE families via microhomology-mediated miniaturization of a Tc1/Mariner element in the yellow fever mosquito.Genome biology and evolution · 2013Article
- Losing identity: structural diversity of transposable elements belonging to different classes in the genome of Anopheles gambiae.BMC genomics · 2012Article
- Burst expansion, distribution and diversification of MITEs in the silkworm genome.BMC genomics · 2010Article
- Article
- A candidate autonomous version of the wheat MITE Hikkoshi is present in the rice genome.Molecular genetics and genomics : MGG · 2005Article
- Tc8, a Tourist-like transposon in Caenorhabditis elegans.Genetics · 2001Article
- Eight novel families of miniature inverted repeat transposable elements in the African malaria mosquito, Anopheles gambiae.Proceedings of the National Academy of Sciences of the United States of America · 2001Article
- Cloning of inversion breakpoints in the Anopheles gambiae complex traces a transposable element at the inversion junction.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
- Three novel families of miniature inverted-repeat transposable elements are associated with genes of the yellow fever mosquito, Aedes aegypti.Proceedings of the National Academy of Sciences of the United States of America · 1997Article
- Distribution of T1, Q, Pegasus and mariner transposable elements on the polytene chromosomes of PEST, a standard strain of Anopheles gambiae.Chromosoma · 1996Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pegasus, a novel transposable element, was discovered as a length polymorphism in the white gene of Anopheles gambiae. Sequence analysis revealed that this 535 bp element was flanked by 8 bp target site duplications and 8 bp perfect terminal inverted repeats similar to those found in many members of the Tc1 family. Its small size and lack of long open reading frames preclude protein coding capacity. Southern analysis and in situ hybridization to polytene chromosomes demonstrated that Pegasus occurs in approximately 30 copies in the genomes of An. gambiae and its sibling species and is homogenous in structure but polymorphic in chromosomal location. Characterization of five additional elements by sequencing revealed nucleotide identities of 95% to 99%. Of 30 Pegasus-containing phage clones examined by PCR, only one contained an element exceeding 535 bp in length, due to the insertion of another transposable element-like sequence. Thus, the majority, if not all, extant Pegasus elements may be defective copies of a complete element whose contemporary existence in An. gambiae is uncertain. No Pegasus-hybridizing sequences were detected in nine other anophelines and three culicines examined, suggesting a very limited taxonomic distribution.
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