Evidence map›Paper›PMID 8975937›Full record

ArticleInfection and immunity1997

Identification and molecular cloning of a 67-kilodalton protein in Schistosoma japonicum homologous to a family of actin-binding proteins.

J D Kurtis, B L Ramirez, P M Wiest, K L Dong, A El-Meanawy, M M Petzke, J H Johnson, J Edmison, R A Maier, G R Olds

Abstract readComparative Study
In one paragraph

Article in Infection and immunity, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

J D KurtisInternational Health Institute, Brown University, Providence, Rhode Island, USA.
B L Ramirez
P M Wiest
K L Dong
A El-Meanawy
M M Petzke
J H Johnson
J Edmison
R A Maier
G R Olds

Funding

VACCINE DEVELOPMENT AGAINST S. JAPONICUMP50AI030601 · NIAID · RESEARCH INSTITUTE FOR TROPICAL MEDICINE · PI OLVEDA, REMIGIOM MEDINA · 1991 to 1995
–
NIAID NIH HHS P50 AI 30601
6 · The paper itself

Abstract

A monoclonal antibody to Schistosoma japonicum which conferred significant protection against cercarial challenge in mice was produced. The predicted translation product of the cDNA corresponding to the antigen recognized by this antibody was homologous to a newly identified family of actin-binding proteins. The expressed protein bound polymerized actin and was recognized by serum from patients infected with S. japonicum.

Indexed as

Cytoskeletal ProteinsAmino Acid SequenceAnimalsAntibodies, HelminthAntibodies, MonoclonalAntigens, HelminthBase SequenceBlood ProteinsCloning, MolecularEzrinHelminth ProteinsImmunization, PassiveMembrane ProteinsMiceMice, Inbred BALB CMicrofilament ProteinsAntibodies, HelminthAntibodies, MonoclonalAntigens, HelminthBlood ProteinsCytoskeletal ProteinsEzrinHelminth ProteinsJF antigen, Schistosoma japonicumMembrane ProteinsMicrofilament ProteinsPhosphoproteinsradixin

Identifiers

PMID8975937
PMCPMC174601

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.