ArticleInfection and immunity1997
Expression and identification of a laminin-binding protein in Aspergillus fumigatus conidia.
Article in Infection and immunity, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 91 citations in OpenAlex.
- Early inflammatory macrophage reprogramming byVirulence · 2026Article
- Emerging Risk Factors for Invasive Pulmonary Aspergillosis: A Narrative Review.Journal of fungi (Basel, Switzerland) · 2025Review
- Review
- A Multifaceted Study of Scedosporium boydii Cell Wall Changes during Germination and Identification of GPI-Anchored Proteins.PloS one · 2015Article
- A soluble fucose-specific lectin from Aspergillus fumigatus conidia--structure, specificity and possible role in fungal pathogenicity.PloS one · 2013Article
- Identification of fibrinogen-binding proteins of Aspergillus fumigatus using proteomic approach.Mycopathologia · 2012Article
- Phage display against corneal epithelial cells produced bioactive peptides that inhibit Aspergillus adhesion to the corneas.PloS one · 2012Article
- Molecular mechanism of Aspergillus fumigatus adherence to host constituents.Current opinion in microbiology · 2011Review
- Melanin is an essential component for the integrity of the cell wall of Aspergillus fumigatus conidia.BMC microbiology · 2009Article
- Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis.Clinical microbiology reviews · 2009Review
- Plasminogen alleles influence susceptibility to invasive aspergillosis.PLoS genetics · 2008Article
- Glyceraldehyde-3-phosphate dehydrogenase of Paracoccidioides brasiliensis is a cell surface protein involved in fungal adhesion to extracellular matrix proteins and interaction with cells.Infection and immunity · 2006Article
- Monoclonal immunoglobulin G1 directed against Aspergillus fumigatus cell wall glycoprotein protects against experimental murine aspergillosis.Clinical and diagnostic laboratory immunology · 2005Article
- Purification and partial characterization of a Paracoccidioides brasiliensis protein with capacity to bind to extracellular matrix proteins.Infection and immunity · 2005Article
- Identification and characterization of polyubiquitin gene from cDNA library of aspergillus fumigatus.Indian journal of clinical biochemistry : IJCB · 2005Article
- Identification of a Treponema pallidum laminin-binding protein.Infection and immunity · 2003Article
- Purification and partial characterization of a 32-kilodalton sialic acid-specific lectin from Aspergillus fumigatus.Infection and immunity · 2002Article
- Protection of killer antiidiotypic antibodies against early invasive aspergillosis in a murine model of allogeneic T-cell-depleted bone marrow transplantation.Infection and immunity · 2002Article
- Aspergillus fumigatus and aspergillosis.Clinical microbiology reviews · 1999Review
- Association of a myosin immunoanalogue with cell envelopes of Aspergillus fumigatus conidia and its participation in swelling and germination.Infection and immunity · 1999Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adhesion of Aspergillus fumigatus, the causative agent of human aspergillosis, to the extracellular matrix protein laminin has been previously demonstrated. This study investigated the expression of laminin receptors during swelling of conidia, a step leading to germination and subsequent colonization of tissues. Scanning electron microscopy showed that the laminin binding sites were distributed over the external rodlet layer of resting conidia. During swelling, the characteristic rodlet layer progressively disintegrated and conidia surrounded by a smooth cell wall layer appeared. Flow cytometry using fluorescein isothiocyanate-conjugated laminin demonstrated that expression of laminin receptors at the surface of conidia was swelling dependent. Resting conidia expressed high levels of laminin receptors on their surface. A gradual decrease of laminin binding was then observed as swelling occurred, reaching a minimum for 4-h-swollen conidia. This correlated with a loss of adherence of swollen conidia to laminin immobilized on microtiter plates. Trypsin pretreatment of conidia reduced laminin binding. Analysis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and ligand blotting with laminin identified in a cell wall extract a major 72-kDa cell wall glycoprotein which binds laminin. Thus, one of the initial events in the host colonization may be the recognition of basement membrane laminin by this 72-kDa cell wall surface component.
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