ArticleJournal of bacteriology1996
Identification and characterization of uvrA, a DNA repair gene of Deinococcus radiodurans.
Article in Journal of bacteriology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Genomic landscape of the human vaginal microbiome is linked to host genetics and population of origin.Nature genetics · 2026Article
- Stable Hypermutators Revealed by the Genomic Landscape of Genes Involved in Genome Stability Among Yeast Species.Molecular biology and evolution · 2025Article
- Draft Genome Sequence ofMicrobiology resource announcements · 2019Article
- Structural and biochemical evidence supporting poly ADP-ribosylation in the bacterium Deinococcus radiodurans.Nature communications · 2019Article
- Conservation and diversity of radiation and oxidative stress resistance mechanisms in Deinococcus species.FEMS microbiology reviews · 2019Review
- Life from the ashes: survival of dry bacterial spores after very high temperature exposure.Extremophiles : life under extreme conditions · 2018Article
- Article
- Genome Sequence of a Gamma- and UV-Ray-Resistant Strain, Deinococcus wulumuqiensis R12.Genome announcements · 2013Article
- Deinococcus radiodurans YgjD and YeaZ are involved in the repair of DNA cross-links.Extremophiles : life under extreme conditions · 2013Article
- Gamma radiation-induced proteome of Deinococcus radiodurans primarily targets DNA repair and oxidative stress alleviation.Molecular & cellular proteomics : MCP · 2012Article
- Oxidative stress resistance in Deinococcus radiodurans.Microbiology and molecular biology reviews : MMBR · 2011Review
- Identification of Vibrio natriegens uvrA and uvrB genes and analysis of gene regulation using transcriptional reporter plasmids.Journal of microbiology (Seoul, Korea) · 2010Article
- Iso-superoxide dismutase in Deinococcus grandis, a UV resistant bacterium.Journal of microbiology (Seoul, Korea) · 2009Article
- Article
- Identification and characterization of two uvrA genes of Xanthomonas axonopodis pathovar citri.Molecular genetics and genomics : MGG · 2007Article
- Article
- Purification and some properties of superoxide dismutase from Deinococcus radiophilus, the UV-resistant bacterium.Extremophiles : life under extreme conditions · 2004Article
- Genetic evidence that the uvsE gene product of Deinococcus radiodurans R1 is a UV damage endonuclease.Journal of bacteriology · 2002Article
- Genome of the extremely radiation-resistant bacterium Deinococcus radiodurans viewed from the perspective of comparative genomics.Microbiology and molecular biology reviews : MMBR · 2001Review
- Ro ribonucleoproteins contribute to the resistance of Deinococcus radiodurans to ultraviolet irradiation.Genes & development · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Deinococcus radiodurans is extraordinarily resistant to DNA damage, because of its unusually efficient DNA repair processes. The mtcA+ and mtcB+ genes of D. radiodurans, both implicated in excision repair, have been cloned and sequenced, showing that they are a single gene, highly homologous to the uvrA+ genes of other bacteria. The Escherichia coli uvrA+ gene was expressed in mtcA and mtcB strains, and it produced a high degree of complementation of the repair defect in these strains, suggesting that the UvrA protein of D. radiodurans is necessary but not sufficient to produce extreme DNA damage resistance. Upstream of the uvrA+ gene are two large open reading frames, both of which are directionally divergent from the uvrA+ gene. Evidence is presented that the proximal of these open reading frames may be irrB+.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.