Evidence map›Paper›PMID 8950557›Full record

GuidelineEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology1996

Classification system and case definitions of Toxoplasma gondii infection in immunocompetent pregnant women and their congenitally infected offspring. European Research Network on Congenital Toxoplasmosis.

M Lebech, D H Joynson, H M Seitz, P Thulliez, R E Gilbert, G N Dutton, B Ovlisen, E Petersen

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In one paragraph

Guideline in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 3 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 3 syntheses or guidelines pooled it, 193 citations in OpenAlex.

  1. Pooled it
  2. Prenatal education for congenital toxoplasmosis.The Cochrane database of systematic reviews · 2015
    Pooled it
  3. Treatments for toxoplasmosis in pregnancy.The Cochrane database of systematic reviews · 2000
    Pooled it
  4. Article
  5. Article
  6. Molecular diagnosis of human toxoplasmosis: the state of the art.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Review
  7. Review
  8. Multicenter evaluation of theJournal of clinical microbiology · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Toxoplasmosis in Germany.Deutsches Arzteblatt international · 2019
    Review
  16. Article
  17. Enzyme-Linked Aptamer Assay (ELAA) for Detection ofFrontiers in cellular and infection microbiology · 2019
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 4 countries.

M LebechLaboratory of Parasitology, Statens Seruminstitut, Copenhagen, Denmark.
D H Joynson
H M Seitz
P Thulliez
R E Gilbert
G N Dutton
B Ovlisen
E Petersen
Statens Serum Institut · DKInstitut de Soudure · FRSingleton Hospital · GBUniversity College Capital · DKUniversity of Bonn · DEUniversity of London · GBWestern Infirmary · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Classification systems and case definitions provide the foundations upon which clinical and epidemiological studies are based. The European Research Network on Congenital Toxoplasmosis acknowledged the lack of such a system or definitions within its field of interest and established a working group to address the issue. Congenital Toxoplasma gondii infection was defined as occurring in four separate patient groups: pregnant women, fetuses, infants, and individuals > 1 year of age. The likelihood of Toxoplasma gondii infection was separated into five mutually exclusive categories: definite, probable, possible, unlikely, and not infected. Inclusion within a specific category is dependent upon the case definition, which is in turn derived from criteria based on serological, parasitological, and clinical information. Notes are included within the classification not only to clarify the definitions, but also to improve the reliability and quality of diagnosis. The goal is to construct a system that encompasses all aspects of congenital toxoplasmosis, which is applicable to different countries and health services, suitable for large epidemiological studies, aids the diagnosis and management of individual cases, and lends itself to computerisation.

Indexed as

FemaleHumansInfant, NewbornInfectious Disease Transmission, VerticalPregnancyPregnancy Complications, ParasiticToxoplasmosis

Identifiers

PMID8950557
OpenAlexW2027109744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.