ArticleProceedings of the National Academy of Sciences of the United States of America1996
myb provides an essential function during Drosophila development.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 37 citations in OpenAlex.
- A long lost key opens an ancient lock:Biology open · 2020Article
- The complex containing Drosophila Myb and RB/E2F2 regulates cytokinesis in a histone H2Av-dependent manner.Molecular and cellular biology · 2013Article
- Duplication and maintenance of the Myb genes of vertebrate animals.Biology open · 2013Article
- The dREAM/Myb-MuvB complex and Grim are key regulators of the programmed death of neural precursor cells at the Drosophila posterior wing margin.Developmental biology · 2012Article
- Epigenetic regulation of olfactory receptor gene expression by the Myb-MuvB/dREAM complex.Genes & development · 2012Article
- Animal-specific C-terminal domain links myeloblastosis oncoprotein (Myb) to an ancient repressor complex.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- The C-MYB story--is it definitive?Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- The Drosophila STIM1 orthologue, dSTIM, has roles in cell fate specification and tissue patterning.BMC developmental biology · 2008Article
- Two components of the Myb complex, DMyb and Mip130, are specifically associated with euchromatin and degraded during prometaphase throughout development.Mechanisms of development · 2008Article
- The epsilon-subunit of mitochondrial ATP synthase is required for normal spindle orientation during the Drosophila embryonic divisions.Genetics · 2005Article
- Functional evolution of the vertebrate Myb gene family: B-Myb, but neither A-Myb nor c-Myb, complements Drosophila Myb in hemocytes.Genetics · 2005Article
- Dm-myb mutant lethality in Drosophila is dependent upon mip130: positive and negative regulation of DNA replication.Genes & development · 2004Article
- Mutation of the Drosophila homologue of the Myb protooncogene causes genomic instability.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- Myb controls G(2)/M progression by inducing cyclin B expression in the Drosophila eye imaginal disc.The EMBO journal · 2002Article
- Physical interaction between CDK9 and B-Myb results in suppression of B-Myb gene autoregulation.Oncogene · 2000Article
- Article
- Drosophila myb is required for the G2/M transition and maintenance of diploidy.Genes & development · 1998Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Vertebrate c-myb encodes a transcription factor thought to play an important role in the cell cycle. To gain further insight into myb function, we have been studying a related gene in Drosophila. We found that Drosophila myb is abundantly expressed throughout development in all mitotically active tissues, at lower levels in some postmitotic tissues, but not at detectable levels in polyploid larval tissues. We performed genetic screens to isolate recessive lethal mutations in the chromosomal region that includes the myb gene. We obtained two temperature-sensitive alleles of myb, demonstrating that the gene provides an essential function. Examination of the mutant phenotype revealed that Drosophila myb is important for both embryonic and imaginal development and that myb serves a role in the development of many tissues and during oogenesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.