Evidence map›Paper›PMID 8940419›Full record

ArticleJournal of clinical microbiology1996

Enteroadherent Escherichia coli and diarrhea in children: a prospective case-control study.

C Forestier, M Meyer, S Favre-Bonte, C Rich, G Malpuech, C Le Bouguenec, J Sirot, B Joly, C De Champs

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

C ForestierLaboratoire de Bactériologie, Faculté de Pharmacie et de Médecine, Université d'Auvergne, Clermont-Ferrand, France. Christiane.Forestier@u-Clermont1.fr
M Meyer
S Favre-Bonte
C Rich
G Malpuech
C Le Bouguenec
J Sirot
B Joly
C De Champs

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The relative contribution of diarrheagenic Escherichia coli was examined during a 1-year prospective study of hospitalized children in Clermont-Ferrand, France, including 220 case patients (with diarrhea) and 211 matched controls. Fecal isolates were characterized by means of their pattern of adherence to HEp-2 cells and by colony hybridization with DNA probes specific for the six categories of diarrheagenic E. coli. No enteroinvasive or enterotoxigenic E. coli isolates were isolated. Twenty-eight (6.5%) eae-positive isolates and 39 (9%) enteroaggregative E. coli isolates characterized with the aggregative adherence probe and/or by their adherence pattern were detected; they were equally distributed among the patients and the controls. Diffusely adhering E. coli was the predominant pathotype: 30.7% were detected by their adherence pattern and 13.7% were detected with the daaC probe. They were isolated with similar frequencies from the patients and the controls, thereby showing no association with diarrhea. However, daaC-positive strains were significantly associated with a past record of urinary tract infections. These results suggest that the diffusely adhering E. coli organisms isolated in the present study are not true intestinal pathogens but may be regarded as resident colonic strains.

Indexed as

AdolescentBacterial AdhesionCase-Control StudiesCell LineChildChild, PreschoolDiarrheaDNA ProbesEscherichia coliEscherichia coli InfectionsFranceHumansInfantInfant, NewbornPolymerase Chain ReactionProspective StudiesDNA Probes

Identifiers

PMID8940419
PMCPMC229430

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.