Evidence map›Paper›PMID 8938648›Full record

ReviewMolecular neurobiology1996

The role of swelling-induced anion channels during neuronal volume regulation.

S Basavappa, J C Ellory

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular neurobiology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. A Biophysical Model for Cytotoxic Cell Swelling.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016
    Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Transient NMDA receptor inactivation provides long-term protection to cultured cortical neurons from a variety of death signals.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2000
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

S BasavappaUniversity Laboratory of Physiology, University of Oxford, UK.
J C Ellory

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regulation of cell volume is an essential function of most mammalian cells. In the cells of the central nervous system, maintenance of cell osmolarity and, hence, volume, is particularly crucial because of the restrictive nature of the skull. Cell volume regulation involves a variety of pathways, with considerable differences between cell types. One common pathway activated during hypo-osmotic stress involves chloride (Cl-) channels. However, hypo-osmotically stimulated anion permeability can be regulated by a diverse array of second messengers. Although neuronal swelling can occur in a number of pathological and nonpathological conditions, our understanding of neuronal volume regulation is limited. This article summarizes our current understanding of the role of anion channels during neuronal volume regulation.

Indexed as

Adenosine TriphosphateAnimalsCalciumCalmodulinCell Membrane PermeabilityCell SizeChloride ChannelsIon Channel GatingMammalsNeuronsOsmotic PressureProtein Kinase CSecond Messenger SystemsAdenosine TriphosphateCalciumCalmodulinChloride ChannelsProtein Kinase C

Identifiers

PMID8938648

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.