ArticleEnvironmental health perspectives1996
Prediction of the rodent carcinogenicity of organic compounds from their chemical structures using the FALS method.
Article in Environmental health perspectives, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- In-vivo and in-vitro toxicity evaluation of 2,3-dimethylquinoxaline: An antimicrobial found in a traditional herbal medicine.PloS one · 2024Article
- Investigation of potential anthropogenic pollution of rare metals in Tama River followed by establishment of a comprehensive multielement analysis of major-to-ultratrace elements in river water and sewage treatment effluent.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2023Article
- Article
- Prediction of genotoxicity of various environmental pollutants by artificial neural network simulation.Molecular diversity · 2006Article
- The NIEHS Predictive-Toxicology Evaluation Project.Environmental health perspectives · 1996Article
- In silico prediction of drug toxicity.Journal of computer-aided molecular designReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fuzzy adaptive least-squares (FALS), a pattern recognition method recently developed in our laboratory for correlating structure with activity rating, was used to generate quantitative structure-activity relationship (QSAR) models on the carcinogenicity of organic compounds of several chemical classes. Using the predictive models obtained from the chemical class-based FALS QSAR approach, the rodent carcinogenicity or noncarcinogenicity of a group of organic chemicals currently being tested by the U.S. National Toxicology Program was estimated from their chemical structures.
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Registered trials
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