ArticleInfection and immunity1996
Induction of Th1 cytokine responses by mycobacterial antigens in leprosy.
Article in Infection and immunity, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Transcription factors STAT-4, STAT-6 and CREB regulate Th1/Th2 response in leprosy patients: effect of M. leprae antigens.BMC infectious diseases · 2019Article
- LiveAmerican journal of translational research · 2018Article
- Mycobacterium leprae-Infected Macrophages Preferentially Primed Regulatory T Cell Responses and Was Associated with Lepromatous Leprosy.PLoS neglected tropical diseases · 2016Article
- HLA and infectious diseases.Clinical microbiology reviews · 2009Review
- The continuing challenges of leprosy.Clinical microbiology reviews · 2006Review
- Cytokine production and lymphocyte proliferation in patients with Nocardia brasiliensis actinomycetoma.Mycopathologia · 2004Article
- Expression of CC and CXC chemokines and chemokine receptors in human leprosy skin lesions.Clinical and experimental immunology · 2003Article
- Novel 33-kilodalton lipoprotein from Mycobacterium leprae.Infection and immunity · 2002Article
- Antigenic specificity of the Mycobacterium leprae homologue of ESAT-6.Infection and immunity · 2002Article
- Results of multiple diagnostic tests for Mycobacterium avium subsp. paratuberculosis in patients with inflammatory bowel disease and in controls.Journal of clinical microbiology · 2000Article
- Article
- Use of a whole blood assay to evaluate in vitro T cell responses to new leprosy skin test antigens in leprosy patients and healthy subjects.Clinical and experimental immunology · 1999Article
- Article
- Leprosy patients with lepromatous disease recognize cross-reactive T cell epitopes in the Mycobacterium leprae 10-kD antigen.Clinical and experimental immunology · 1998Article
- Changes in cellular response to mycobacterial antigens and cytokine production patterns in leprosy patients during multiple drug therapy.Immunology · 1998Article
- Setaria digitata adult 14- to 20-kDa antigens induce differential Th1/Th2 cytokine responses in the lymphocytes of endemic normals and asymptomatic microfilariae carriers in bancroftian filariasis.Journal of clinical immunology · 1998Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Twelve mycobacterial antigens were compared for induction of gamma interferon (IFN-gamma) secretion by human blood mononuclear cells of patients with leprosy. Fractionated Mycobacterium leprae antigens containing cell wall proteins or cytosolic and membrane proteins induced good IFN-gamma responses in tuberculoid leprosy patients. Lipoarabinomannan from M. tuberculosis Erdman and M. leprae mycolylarabinogalactan peptidoglycan were the poorest IFN-gamma inducers.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.