ReviewBehavior genetics1996
Searching for candidate genes with effects on an agonistic behavior, offense, in mice.
Review in Behavior genetics, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 67 citations in OpenAlex.
- Sex-limited chromosomes and non-reproductive traits.BMC biology · 2022Review
- Mouse model systems to study sex chromosome genes and behavior: relevance to humans.Frontiers in neuroendocrinology · 2014Review
- Natural genetic variation underlying differences in Peromyscus repetitive and social/aggressive behaviors.Behavior genetics · 2014Article
- Gene expression in aminergic and peptidergic cells during aggression and defeat: relevance to violence, depression and drug abuse.Behavior genetics · 2011Review
- Neural stem cell sex dimorphism in aromatase (CYP19) expression: a basis for differential neural fate.Stem cells and cloning : advances and applications · 2010Article
- Ontological Discovery Environment: a system for integrating gene-phenotype associations.Genomics · 2009Article
- Mouse models for evaluating sex chromosome effects that cause sex differences in non-gonadal tissues.Journal of neuroendocrinology · 2009Review
- The Role of the Y Chromosome in Brain Function.Open neuroendocrinology journal (Online) · 2009Article
- Neurobiology of escalated aggression and violence.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2007Review
- Disruption of the vasopressin 1b receptor gene impairs the attack component of aggressive behavior in mice.Genes, brain, and behavior · 2007Article
- Review
- Prostate cancer incidence varies among males from different Y-chromosome lineages.Prostate cancer and prostatic diseases · 2006Article
- A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2002Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is well established that the agonistic behavior of offense in mice is heritable. However, few genes have been identified or mapped for offense. For segments of chromosomes with effects on offense, a positional candidate strategy can be used to find such genes. This approach is illustrated for the effect of the male specific part (nonpseudoautosomal region; NPAR) of the mouse Y chromosome on offense. It is proposed that a positional candidate for this effect is Sry. The Sry protein is a transcription factor. Its mRNA is expressed in fetal and adult brain. Its protein binds to response elements in the 5' end of the aromatase and the Fra1 genes. Each of these genes has potential effects on several brain neurotransmitter systems involved in offense. The NPAR Y chromosomes of several pairs of inbred strains have differential effects on offense. This hypothesis would be tested by sequencing Sry for some of these pairs of strains.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.