ArticleGenetics1996
Induction of Ty recombination in yeast by cDNA and transcription: role of the RAD1 and RAD52 genes.
Article in Genetics, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Genetic Characterization of Three Distinct Mechanisms Supporting RNA-Driven DNA Repair and Modification Reveals Major Role of DNA Polymerase ζ.Molecular cell · 2020Article
- Review
- Formation of Extrachromosomal Circular DNA from Long Terminal Repeats of Retrotransposons in Saccharomyces cerevisiae.G3 (Bethesda, Md.) · 2015Article
- Retrotransposon suicide: formation of Ty1 circles and autointegration via a central DNA flap.Journal of virology · 2006Article
- Transcription and double-strand breaks induce similar mitotic recombination events in Saccharomyces cerevisiae.Genetics · 2002Article
- Genetic requirements for spontaneous and transcription-stimulated mitotic recombination in Saccharomyces cerevisiae.Genetics · 2002Article
- Drosophila euchromatic LTR retrotransposons are much younger than the host species in which they reside.Genome research · 2001Article
- The Saccharomyces cerevisiae DNA recombination and repair functions of the RAD52 epistasis group inhibit Ty1 transposition.Genetics · 2000Article
- cDNA of the yeast retrotransposon Ty5 preferentially recombines with substrates in silent chromatin.Molecular and cellular biology · 1999Article
- Schizosaccharomyces pombe retrotransposon Tf2 mobilizes primarily through homologous cDNA recombination.Molecular and cellular biology · 1998Article
- The involvement of cellular recombination and repair genes in RNA-mediated recombination in Saccharomyces cerevisiae.Genetics · 1998Article
- High frequency cDNA recombination of the saccharomyces retrotransposon Ty5: The LTR mediates formation of tandem elements.Genetics · 1997Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the yeast Saccharomyces cerevisiae ectopic recombination has been shown to occur at high frequencies for artificially created repeats, but at relatively low frequencies for a natural family of repeated sequences, the Ty family. Little is known about the mechanism(s) that prevent recombination between repeated sequences. We have previously shown that nonreciprocal recombination (gene conversion) of a genetically marked Ty can be induced either by the presence of high levels of Ty cDNA or by transcription of the marked Ty from a GAL1 promoter. These two kinds of induction act in a synergistic manner. To further characterize these two kinds of Ty recombination, we have investigated the role played by the RAD52 and RAD1 genes. We have found that the RAD52 and RAD1 gene products are essential to carry out transcription-induced Ty conversion whereas cDNA-mediated conversion can take place in their absence.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.