ReviewWorld journal of urology1996
Mesenchymal-epithelial interactions in the bladder.
Review in World journal of urology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 57 citations in OpenAlex.
- Rewriting the urinary tract paradigm: the urobiome as a gatekeeper of host defense.Molecular biology reports · 2025Review
- Inhibition of LIM kinase reduces contraction and proliferation in bladder smooth muscle.Acta pharmaceutica Sinica. B · 2021Article
- Tissue-Specific Localization NUCB2/nesfatin-1 in the Liver and Heart of Mouse Fetus.Development & reproduction · 2018Article
- Single-cell RNA-seq analysis unveils a prevalent epithelial/mesenchymal hybrid state during mouse organogenesis.Genome biology · 2018Article
- Maintenance of bladder urothelia integrity and successful urothelialization of various tissue-engineered mesenchymes in vitro.In vitro cellular & developmental biology. Animal · 2015Article
- Lack of nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2): consequences for mouse bladder development and function.Neurourology and urodynamics · 2013Article
- Spatio-temporal distribution of Smads and role of Smads/TGF-β/BMP-4 in the regulation of mouse bladder organogenesis.PloS one · 2013Article
- Analysis of the Sonic Hedgehog signaling pathway in normal and abnormal bladder development.PloS one · 2013Article
- Mechanical strain activates a program of genes functionally involved in paracrine signaling of angiogenesis.Physiological genomics · 2008Article
- Urothelium patterns bladder smooth muscle location.Pediatric research · 2008Article
- Directed differentiation of bone marrow derived mesenchymal stem cells into bladder urothelium.The Journal of urology · 2008Article
- Mesenchymal-epithelial interaction techniques.Differentiation; research in biological diversityReview
- Urothelium-derived Sonic hedgehog promotes mesenchymal proliferation and induces bladder smooth muscle differentiation.Differentiation; research in biological diversityArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
During bladder development, undifferentiated mesenchymal and epithelial cells undergo an orderly sequence of differentiation defined by the expression of smooth-muscle (alpha-actin, myosin, vinculin, desmin, vimentin, and laminin) and epithelial (cytokeratins 5, 7, 8, 14, 18 and 19) protein markers. This process requires mesenchymal-epithelial interactions with bladder epithelium (urothelium) necessary for the differentiation of bladder smooth muscle. Peptide growth factors such as keratinocyte growth factor (KGF) and transforming growth factors (TGF) alpha and beta are likely candidates as mediators of these mesenchymal-epithelial interactions. Transcripts for KGF, TGF alpha, and TGF beta are regulated during bladder development and during smooth-muscle hypertrophy secondary to bladder-outlet obstruction. Finally, two experimental bladder models--(1) partial outlet obstruction and (2) regeneration of bladder smooth muscle into an acellular tissue matrix--are described in the context of mesenchymal-epithelial interactions in the bladder.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.