ArticleMammalian genome : official journal of the International Mammalian Genome Society1996
Cardiac and skeletal muscle troponin I isoforms are encoded by a dispersed gene family on mouse chromosomes 1 and 7.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 21 citations in OpenAlex.
- Real-time reverse transcription-PCR expression profiling of porcine troponin I family in three different types of muscles during development.Molecular biology reports · 2011Article
- Identification of three novel SNPs and association with carcass traits in porcine TNNI1 and TNNI2.Molecular biology reports · 2010Article
- Culture on electrospun polyurethane scaffolds decreases atrial natriuretic peptide expression by cardiomyocytes in vitro.Biomaterials · 2008Article
- Characterization of the mouse adeno-associated virus AAVS1 ortholog.Journal of virology · 2004Article
- Structure and regulation of human troponin genes.Molecular and cellular biochemistry · 2004Article
- A genomewide survey of developmentally relevant genes in Ciona intestinalis. IX. Genes for muscle structural proteins.Development genes and evolution · 2003Article
- Assembly of force-expressed troponin-I isoforms in myofibrils of cultured cardiac and fast skeletal muscle cells as studied by epitope tagging.Journal of muscle research and cell motility · 1998Article
- cDNA cloning and chromosomal mapping of mouse fast skeletal muscle troponin T.Mammalian genome : official journal of the International Mammalian Genome Society · 1997Article
- Strong evolutionary conservation of broadly expressed protein isoforms in the troponin I gene family and other vertebrate gene families.Journal of molecular evolution · 1996Article
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
Abstract
We mapped the locations of the genes encoding the slow skeletal muscle, fast skeletal muscle, and cardiac isoforms of troponin I (Tnni) in the mouse genome by interspecific hybrid backcross analysis of species-specific (C57BL/6 vs Mus spretus) restriction fragment length polymorphisms (RFLPs). The slow skeletal muscle troponin I locus (Tnni1) mapped to Chromosome (Chr) 1. The fast skeletal muscle troponin I locus (Tnni2), mapped to Chr 7, approximately 70 cM from the centromere. The cardiac troponin I locus (Tnni3) also mapped to Chr 7, approximately 5-10 cM from the centromere and unlinked to the fast skeletal muscle troponin I locus. Thus, the troponin I gene family is dispersed in the mouse genome.
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