ReviewCurrent opinion in immunology1996
The new vaccines: building viruses that elicit antitumor immunity.
Review in Current opinion in immunology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 72 citations in OpenAlex.
- Influence of tumors on protective anti-tumor immunity and the effects of irradiation.Frontiers in oncology · 2013Article
- Immunochemical termination of self-tolerance.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- Escape from immunotherapy: possible mechanisms that influence tumor regression/progression.Cancer immunology, immunotherapy : CII · 2004Review
- Cancer vaccines: progress reveals new complexities.The Journal of clinical investigation · 2002Review
- Prime-boost vaccines encoding an intracellular idiotype/GM-CSF fusion protein induce protective cell-mediated immunity in murine pre-B cell leukemia.Gene therapy · 2002Article
- Adenovirus-transduced dendritic cells stimulate cellular immunity to melanoma via a CD4(+) T cell-dependent mechanism.Gene therapy · 2001Article
- Challenges to the development of antigen-specific breast cancer vaccines.Breast cancer research : BCR · 2001Review
- Creating therapeutic cancer vaccines: notes from the battlefield.Trends in immunology · 2001Article
- Immunogenicity of enhanced green fluorescent protein (EGFP) in BALB/c mice: identification of an H2-Kd-restricted CTL epitope.Gene therapy · 2000Article
- Recombinant yellow fever viruses are effective therapeutic vaccines for treatment of murine experimental solid tumors and pulmonary metastases.Journal of virology · 2000Article
- Cutting edge: CD4+ T cell control of CD8+ T cell reactivity to a model tumor antigen.Journal of immunology (Baltimore, Md. : 1950) · 2000Article
- The promise of nucleic acid vaccines.Gene therapy · 2000Review
- Induction of P815 tumor immunity by recombinant Semliki Forest virus expressing the P1A gene.Gene therapy · 1999Article
- Cancer therapy using a self-replicating RNA vaccine.Nature medicine · 1999Article
- Article
- Developing recombinant and synthetic vaccines for the treatment of melanoma.Current opinion in oncology · 1999Review
- Transfectant influenza A viruses are effective recombinant immunogens in the treatment of experimental cancer.Virology · 1998Article
- gp100/pmel 17 is a murine tumor rejection antigen: induction of "self"-reactive, tumoricidal T cells using high-affinity, altered peptide ligand.The Journal of experimental medicine · 1998Article
- Molecular cancer vaccines: Tumor therapy using antigen-specific immunizations.Pathology oncology research : POR · 1997Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Whereas cancer cells are poor immunogens, some viruses are capable of eliciting powerful and lifelong immunity. Recombinant viruses and plasmid DNA encoding tumor-associated antigens can elicit powerful and specific immune responses that can be enhanced by the use of cytokines and costimulatory molecules. These immune responses have destroyed growing tumor cells in experimental animal models. For the first time, immunotherapeutic strategies that employ recombinant viruses are being tested in clinical trials with cancer patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.