ReviewPediatric nephrology (Berlin, Germany)1996
Glycosaminoglycans, proteins, and stone formation: adult themes and child's play.
Review in Pediatric nephrology (Berlin, Germany), 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 60 citations in OpenAlex.
- Advances in the mechanism of urinary proteins in calcium oxalate kidney stone formation.Urolithiasis · 2025Review
- Stress-stones-stress-recurrent stones: a self-propagating cycle? Difficulties in solving this dichotomy.Urolithiasis · 2017Article
- Kinetics of calcium oxalate crystal formation in urine.Urolithiasis · 2017Article
- The role of macromolecules in the formation of kidney stones.Urolithiasis · 2017Review
- Nephrolithiasis: molecular mechanism of renal stone formation and the critical role played by modulators.BioMed research international · 2013Review
- Toward a structure determination method for biomineral-associated protein using combined solid- state NMR and computational structure prediction.Structure (London, England : 1993) · 2010Article
- A novel calcium oxalate crystal growth inhibitory protein from the seeds of Dolichos biflorus (L.).The protein journal · 2009Article
- Variability of protein content in calcium oxalate monohydrate stones.Journal of endourology · 2006Article
- Pediatric urolithiasis: etiology, specific pathogenesis and medical treatment.Urological research · 2006Review
- Identification of human urinary trefoil factor 1 as a novel calcium oxalate crystal growth inhibitor.The Journal of clinical investigation · 2005Article
- Urinary inhibitors of calcium oxalate crystallization and their potential role in stone formation.World journal of urology · 1997Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The relative infrequency of renal stones in children is probably the main reason for the paucity of literature devoted to the study of urolithiasis in pediatric patients. Nonetheless, when pediatricians do address the issue, the contents of their papers reflect those prevalent in the adult literature; with one notable exception. Papers dealing with the potential role of urinary macromolecules in pediatric stone disease are very scarce indeed; to my knowledge, only four have been published in the English literature in the last 15 years. One of these is to be found in this issue and, like the remaining three, it compares the urinary excretion of glycosaminoglycans in healthy children and those with stones. This article briefly reviews the history of the association of urinary macromolecules, particularly glycosaminoglycans and proteins, with calcium oxalate urolithiasis, and discusses in more detail the published experimental evidence for their fulfilling a determinant role in stone formation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.