Evidence map›Paper›PMID 8897198›Full record

ArticleJournal of clinical microbiology1996

Comparison of rapid testing methods for enzyme production with the germ tube method for presumptive identification of Candida albicans.

J S Heelan, D Siliezar, K Coon

Abstract readComparative Study
In one paragraph

Article in Journal of clinical microbiology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Candida parapsilosis : an emerging fungal pathogen.The Indian journal of medical research · 2012
    Article
  3. Article
  4. Article
  5. Comparison of a new chromogenic agar with the germ tube method for presumptive identification of Candida albicans.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 1998
    Article
  6. Rapid detection of Candida species in bronchoalveolar lavage fluid from patients with pulmonary symptoms.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

J S HeelanDepartment of Pathology, Memorial Hospital of Rhode Island, Pawtucket 02860, USA.
D Siliezar
K Coon

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The observation of germ tube production as a method for the presumptive identification of Candida albicans has been in use for many years. Methods have recently been developed for detecting the production of the enzymes L-proline aminopeptidase and beta-galactosaminidase by yeast isolates grown in culture. Both enzymes are produced by C. albicans; other yeasts may produce either L-proline aminopeptidase or beta-galactosaminidase but not both enzymes. One hundred thirty-three clinical yeast isolates, including 55 C. albicans, 27 Candida tropicalis, 22 Torulopsis (Candida) glabrata, and 29 other yeast isolates were tested by the germ tube production method and three tests for enzyme production, with the API 20C method used as a "gold standard." All three enzymatic methods evaluated provided more objective and rapid nonmicroscopic alternatives to the germ tube test and may be used to accurately distinguish C. albicans from other yeasts.

Indexed as

AminopeptidasesCandidaCandida albicansCandidiasisEvaluation Studies as TopicHexosaminidasesHumansMycologyReference StandardsSpecies SpecificityYeastsAminopeptidasesHexosaminidasesprolyl aminopeptidase

Identifiers

PMID8897198
PMCPMC229419

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.