ReviewThe Histochemical journal1996
Bromodeoxyuridine: a diagnostic tool in biology and medicine, Part III. Proliferation in normal, injured and diseased tissue, growth factors, differentiation, DNA replication sites and in situ hybridization.
Review in The Histochemical journal, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 95 citations in OpenAlex.
- Beneficial effects of melatonin combined with exercise on endogenous neural stem/progenitor cells proliferation after spinal cord injury.International journal of molecular sciences · 2014Article
- 5-HT receptors mediate lineage-dependent effects of serotonin on adult neurogenesis in Procambarus clarkii.Neural development · 2011Article
- Functional electrical stimulation helps replenish progenitor cells in the injured spinal cord of adult rats.Experimental neurology · 2010Article
- A fast and robust hepatocyte quantification algorithm including vein processing.BMC bioinformatics · 2010Article
- Enhanced sensitivity of the MRL/MpJ mouse to the neuroplastic and behavioral effects of acute and chronic antidepressant treatments.Experimental and clinical psychopharmacology · 2010Article
- Statistical and economical efficiency in assessment of liver regeneration using defined sample size and selection in combination with a fully automated image analysis system.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2009Article
- Adult neurogenesis in the crayfish brain: proliferation, migration, and possible origin of precursor cells.Developmental neurobiology · 2009Article
- Histological assessment of cellular half-life in tissues in vivo.Histochemistry and cell biology · 2008Article
- Role of E2F3 expression in modulating cellular proliferation rate in human bladder and prostate cancer cells.Oncogene · 2007Article
- Insulin reduces apoptosis and increases DNA synthesis and cell size via distinct signalling pathways in Drosophila Kc cells.Cell proliferation · 2004Article
- Identification of dynamically distinct subpopulations of T lymphocytes that are differentially affected by HIV.The Journal of experimental medicine · 2001Article
- Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat.Proceedings of the National Academy of Sciences of the United States of America · 2001Article
- Optimized fluorescent probe combinations for evaluation of proliferation and necrosis in anthracycline-treated leukaemic cell lines.Cell proliferation · 1999Article
- From embryo to adult: persistent neurogenesis and apoptotic cell death shape the lobster deutocerebrum.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1999Article
- Replicon clusters are stable units of chromosome structure: evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells.The Journal of cell biology · 1998Article
- Regulation and disregulation of mammalian nucleotide excision repair: a pathway to nongermline breast carcinogenesis.Photochemistry and photobiologyArticle
- Flow cytometric analysis of BrdU incorporation as a high-throughput method for measuring adult neurogenesis in the mouse.Journal of pharmacological and toxicological methodsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper is a continuation of parts I (history, methods and cell kinetics) and II (clinical applications and carcinogenesis) published previously (Dolbeare, 1995 Histochem. J. 27, 339, 923). Incorporation of bromodeoxyuridine (BrdUrd) into DNA is used to measure proliferation in normal, diseased and injured tissue and to follow the effect of growth factors. Immunochemical detection of BrdUrd can be used to determine proliferative characteristics of differentiating tissues and to obtain birth dates for actual differentiation events. Studies are also described in which BrdUrd is used to follow the order of DNA replication in specific chromosomes, DNA replication sites in the nucleus and to monitor DNA repair. BrdUrd incorporation has been used as a tool for in situ hybridization experiments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.