ArticleExperimental brain research1996
Responses of medullary reticulospinal neurones to stimulation of cutaneous limb nerves during locomotion in intact cats.
Article in Experimental brain research, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 51 citations in OpenAlex.
- Changes in intra- and interlimb reflexes from hindlimb cutaneous afferents after staggered thoracic lateral hemisections during locomotion in cats.The Journal of physiology · 2024Article
- Excitatory and Inhibitory Descending Commissural Interneurons Differentially Integrate Supraspinal and Segmental Sensory Signals.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- The connectome of an insect brain.Science (New York, N.Y.) · 2023Article
- State- and Condition-Dependent Modulation of the Hindlimb Locomotor Pattern in Intact and Spinal Cats Across Speeds.Frontiers in systems neuroscience · 2022Article
- Control of Mammalian Locomotion by Somatosensory Feedback.Comprehensive Physiology · 2021Article
- Extensive Cortical Convergence to Primate Reticulospinal Pathways.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Axial reflexes are present in older subjects and may contribute to balance responses.Experimental brain research · 2018Article
- Reticulospinal Systems for Tuning Motor Commands.Frontiers in neural circuits · 2018Review
- Sensorimotor anatomy of gait, balance, and falls.Handbook of clinical neurology · 2018Review
- Supraspinal Control Predicts Locomotor Function and Forecasts Responsiveness to Training after Spinal Cord Injury.Journal of neurotrauma · 2017Review
- Neurons in the pontomedullary reticular formation receive converging inputs from the hindlimb and labyrinth.Experimental brain research · 2017Article
- Origin of directionally tuned responses in lower limb muscles to unpredictable upper limb disturbances.PloS one · 2017Article
- Descending Influences on Vestibulospinal and Vestibulosympathetic Reflexes.Frontiers in neurology · 2017Review
- Modulation of spinal motor output by initial arm postures in anesthetized monkeys.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Decoding hindlimb movement for a brain machine interface after a complete spinal transection.PloS one · 2012Article
- Behavioral response and transmitter release during atonia elicited by medial medullary stimulation.Journal of neurophysiology · 2010Article
- Soleus H-reflex modulation during body weight support treadmill walking in spinal cord intact and injured subjects.Experimental brain research · 2009Article
- Brainstem modulation of locomotion in the neonatal mouse spinal cord.The Journal of physiology · 2008Article
- Movement-related and preparatory activity in the reticulospinal system of the monkey.Experimental brain research · 2004Article
- A cellular mechanism for the transformation of a sensory input into a motor command.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2000Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study was designed to determine whether the transmission of cutaneous afferent information from the limbs to the medullary reticular formation is phasically modulated during locomotion. Experiments were carried out in three chronically prepared, intact cats in which nerve cuff electrodes were placed, bilaterally, on the superficial radial and the superficial peroneal nerves. Thirty-seven reticulospinal neurones (RSNs) were identified by stimulation of their axons in the lumbar spinal cord (L2); 29 of 37 of these were recorded with the cat at rest, 28 of 37 during locomotion and 20 of 37 both at rest and during locomotion. Low-threshold stimulation of the cutaneous nerves evoked excitatory responses in the majority of RSNs both at rest and during locomotion. In the 28 of 37 RSNs recorded during locomotion, it was possible to record the evoked response to stimulation of all four limb nerves, giving a total of 184 tested cases [RSNs tested x number of nerves stimulated x phase of stimulation (swing or stance)]. The responses of most RSNs to cutaneous stimulation were modulated in a phase-dependent manner during locomotion. The maximal responses in most, but not all, cases were obtained during the swing phase of the limb that was stimulated and were largely independent of the discharge pattern of the cell. We interpret this result as indicating that the efficacy of transmission of the afferent information is determined more by the excitability of the spinal relay neurones than by the level of excitability of the RSNs in the brainstem. It is suggested that the base discharge pattern of RSNs might be largely determined by their central afferent input, while peripheral afferent inputs would primarily serve to modify the RSN discharge pattern in response to perturbations.
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