ArticleBiophysical journal1996
Similarity in calcium channel activity of annexin V and matrix vesicles in planar lipid bilayers.
Article in Biophysical journal, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 93 citations in OpenAlex.
- A new look at Hsp70 activity in phosphatidylserine-enriched membranes: chaperone-induced quasi-interdigitated lipid phase.Scientific reports · 2023Article
- Article
- Avian eggshell formation reveals a new paradigm for vertebrate mineralization via vesicular amorphous calcium carbonate.The Journal of biological chemistry · 2020Article
- Localization of Annexin A6 in Matrix Vesicles During Physiological Mineralization.International journal of molecular sciences · 2020Article
- The small heat shock proteins, HSPB1 and HSPB5, interact differently with lipid membranes.Cell stress & chaperones · 2019Article
- Calcium Regulates the Nuclear Localization of Protein Arginine Deiminase 2.Biochemistry · 2019Article
- Expression and function of Slc34 sodium-phosphate co-transporters in skeleton and teeth.Pflugers Archiv : European journal of physiology · 2019Review
- Proteoliposomes in nanobiotechnology.Biophysical reviews · 2012Review
- Extracellular heat shock proteins, cellular export vesicles, and the Stress Observation System: a form of communication during injury, infection, and cell damage. It is never known how far a controversial finding will go! Dedicated to Ferruccio Ritossa.Cell stress & chaperones · 2011Review
- Proteoliposomes as matrix vesicles' biomimetics to study the initiation of skeletal mineralization.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2010Review
- Role of matrix vesicles in biomineralization.Biochimica et biophysica acta · 2009Review
- Zea mays annexins modulate cytosolic free Ca2+ and generate a Ca2+-permeable conductance.The Plant cell · 2009Article
- Structure of human annexin a6 at the air-water interface and in a membrane-bound state.Biophysical journal · 2004Article
- Architecture of the Alzheimer's A beta P ion channel pore.The Journal of membrane biology · 2004Article
- DT40 cells lacking the Ca2+-binding protein annexin 5 are resistant to Ca2+-dependent apoptosis.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- GTP-induced membrane binding and ion channel activity of annexin VI: is annexin VI a GTP biosensor?Biophysical journal · 2002Article
- Expression of early and late differentiation markers (proliferating cell nuclear antigen, syndecan-3, annexin VI, and alkaline phosphatase) by human osteoarthritic chondrocytes.The American journal of pathology · 2001Article
- Annexins V and XII alter the properties of planar lipid bilayers seen by conductance probes.The Journal of general physiology · 2000Article
- Localization of the apoptosis-inducing activity of lupus anticoagulant in an annexin V-binding antibody subset.The Journal of clinical investigation · 1998Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Matrix vesicles (MVs), structures that accumulate Ca2+ during the initiation of mineral formation in growing bone, are rich in annexin V. When MVs are fused with planar phospholipid bilayers, a multiconductance Ca2+ channel is formed, with activity essentially identical to that observed when annexin V is delivered to the bilayer with phosphatidylserine liposomes. Ca2+ currents through this channel, from either MV or annexin V liposomes, are blocked by Zn2+, as is Ca2+ uptake by MV incubated in synthetic cartilage lymph. Blockage by Zn2+ was most effective when applied to the side containing the MV or liposomes. ATP and GTP differentially modulated the activity of this channel: ATP increased the amplitude of the current and the number of conductance states; GTP dramatically reduced the number of events and conductance states, leading to well-defined Ca2+ channel activity from either MV or the annexin V liposomes. In the distinctive effects of ATP, GTP, and Zn2+ on the Ca2+ channel activity observed in both the MV and the liposome systems, the common factor was the presence of annexin V. From this we conclude that Ca2+ entry into MV results from the presence of annexin V in these membrane-enclosed structures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.