ArticleBritish journal of pharmacology1996
Influence of contractile agonists on the mechanism of endothelium-dependent relaxation in rat isolated mesenteric artery.
Article in British journal of pharmacology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 55 citations in OpenAlex.
- Vasoconstrictor stimulus determines the functional contribution of myoendothelial feedback to mesenteric arterial tone.The Journal of physiology · 2018Article
- PDE1A inhibition elicits cGMP-dependent relaxation of rat mesenteric arteries.British journal of pharmacology · 2017Article
- Novel selective PDE type 1 inhibitors cause vasodilatation and lower blood pressure in rats.British journal of pharmacology · 2017Article
- Article
- Motility of the ureter of the spontaneously hypertensive rat.Irish journal of medical science · 2011Article
- Openers of small conductance calcium-activated potassium channels selectively enhance NO-mediated bradykinin vasodilatation in porcine retinal arterioles.British journal of pharmacology · 2010Article
- Evidence against C-type natriuretic peptide as an arterial 'EDHF'.British journal of pharmacology · 2008Article
- Thromboxane A2 inhibition of SKCa after NO synthase block in rat middle cerebral artery.British journal of pharmacology · 2007Article
- Elevated pressure selectively blunts flow-evoked vasodilatation in rat mesenteric small arteries.British journal of pharmacology · 2007Article
- Cardiovascular pharmacology of cannabinoids.Handbook of experimental pharmacology · 2005Review
- Thromboxane receptor stimulation associated with loss of SKCa activity and reduced EDHF responses in the rat isolated mesenteric artery.British journal of pharmacology · 2004Article
- Different modulation by Ca2+-activated K+ channel blockers and herbimycin of acetylcholine- and flow-evoked vasodilatation in rat mesenteric small arteries.British journal of pharmacology · 2003Article
- Endothelium-derived hyperpolarizing factor and potassium use different mechanisms to induce relaxation of human subcutaneous resistance arteries.British journal of pharmacology · 2001Article
- Mechanisms of 17 beta-oestradiol induced vasodilatation in isolated pressurized rat small arteries.British journal of pharmacology · 2000Article
- Potentiation of cyclic AMP-mediated vasorelaxation by phenylephrine in pulmonary arteries of the rat.British journal of pharmacology · 1999Article
- Mechanisms of hypoxic vasodilatation of isolated rat mesenteric arteries: a comparison with metabolic inhibition.The Journal of physiology · 1999Article
- Mechanisms underlying ACh induced modulation of neurogenic and applied ATP constrictions in the submucosal arterioles of the guinea-pig small intestine.British journal of pharmacology · 1999Article
- Endothelium-dependent hyperpolarization in resting and depolarized mammary and coronary arteries of guinea-pigs.British journal of pharmacology · 1999Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
This study demonstrates directly that the relative contribution of nitric oxide (NO) and an NO synthase-independent repolarization to acetylcholine-evoked relaxation in rat isolated mesenteric resistance arteries is determined by the processes which mediate pre-contraction. Noradrenaline-induced contractions were reversed by acetylcholine via both NO and NO synthase-independent smooth muscle repolarization. In contrast, reversal of contractions to the thromboxane-mimetic, U46619, by acetylcholine was entirely mediated by the actions of NO, independently of a change in membrane potential.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.