ReviewJournal of inherited metabolic disease1996
Mitochondrial encephalomyopathies: what next?
Review in Journal of inherited metabolic disease, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Moyamoya syndrome secondary to MELAS syndrome in a child: A case report and literature revue.Radiology case reports · 2024Article
- Article
- Adaptive optimization of the OXPHOS assembly line partially compensates lrpprc-dependent mitochondrial translation defects in mice.Communications biology · 2021Article
- Neuroradiologic findings in children with mitochondrial disorder: correlation with mitochondrial respiratory chain defects.European radiology · 2008Article
- The mitochondrial myopathy encephalopathy, lactic acidosis with stroke-like episodes (MELAS) syndrome: a review of treatment options.CNS drugs · 2006Review
- Phenotype variability in 130 adult patients with respiratory chain disorders.Journal of inherited metabolic disease · 2001Article
- 3-Methylglutaconic aciduria and hypermethioninaemia in a child with clinical and neuroradiological findings of Leigh disease.Journal of inherited metabolic disease · 1999Article
- Retrograde Ca2+ signaling in C2C12 skeletal myocytes in response to mitochondrial genetic and metabolic stress: a novel mode of inter-organelle crosstalk.The EMBO journal · 1999Article
- Mitochondrial DNA mutations and mitochondrial abnormalities in dilated cardiomyopathy.The American journal of pathology · 1998Article
- Mitochondrial disorders.The Japanese journal of human genetics · 1997Review
- Treatment of mitochondrial disease.Journal of bioenergetics and biomembranes · 1997Review
- Genetic counselling and prenatal diagnosis in disorders of the mitochondrial energy metabolism.Journal of inherited metabolic disease · 1996Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
In few areas of medicine has progress been more spectacular than in the field of mitochondrial diseases, especially those related to mtDNA mutations. Much remains to be done, however, and this brief review discusses the following areas of research where progress has been more limited or data are still controversial: (1) the molecular basis of respiratory-chain defects due to nuclear DNA mutations; (2) defects of mitochondrial protein importation; (3) defects of intergenomic signalling; (4) pathophysiology of mtDNA-related disorders; (5) ageing and age-related neurodegenerative diseases; (6) therapy; and (7) genetic counselling.
Indexed as
Identifiers
8884573What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.