ArticleJournal of clinical microbiology1996
Multicentric epidemiological study of Aspergillus fumigatus isolates by multilocus enzyme electrophoresis.
Article in Journal of clinical microbiology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 32 citations in OpenAlex.
- Review
- Multilocus enzyme electrophoresis: a practical guide.Molecular biotechnology · 2003Article
- Differentiation between isolates of Aspergillus fumigatus from breeding turkeys and their environment by genotyping with microsatellite markers.Journal of clinical microbiology · 2003Article
- Evaluation of performance of four genotypic methods for studying the genetic epidemiology of Aspergillus fumigatus isolates.Journal of clinical microbiology · 2002Article
- Disease surveillance in recombining pathogens: multilocus genotypes identify sources of human Coccidioides infections.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- Genetic structure of Candida glabrata populations in AIDS and non-AIDS patients.Journal of clinical microbiology · 2002Article
- Epidemiology and Prevention of Invasive Aspergillosis.Current infectious disease reports · 2001Article
- Genetic polymorphism of Aspergillus fumigatus in clinical samples from patients with invasive aspergillosis: investigation using multiple typing methods.Journal of clinical microbiology · 2001Article
- The ins and outs of DNA fingerprinting the infectious fungi.Clinical microbiology reviews · 2000Review
- Aspergillus fumigatus and aspergillosis.Clinical microbiology reviews · 1999Review
- Genetic multilocus studies of different strains of Cryptococcus neoformans: taxonomy and genetic structure.Journal of clinical microbiology · 1999Article
- The evolutionary biology and population genetics underlying fungal strain typing.Clinical microbiology reviews · 1999Review
- Molecular typing of environmental and patient isolates of Aspergillus fumigatus from various hospital settings.Journal of clinical microbiology · 1998Article
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The genotypes of 63 isolates of Aspergillus fumigatus obtained from three hospitals in different geographical areas and of eight culture collection strains were determined by multilocus enzyme electrophoresis. Twelve of the 17 enzymatic loci studied were polymorphic, giving rise to 48 different electrophoretic types. The existence of fixed multilocus genotypes, significant heterozygote deficits and excesses at the different loci, and linkage disequilibria within subpopulations strongly suggests a clonal reproduction mode for A. fumigatus. Numerical analysis of the comparison and disposition of the different electrophoretic types demonstrates a significant genetic differentiation between the three sampling sites. However, no correlation could be found between geographical distances and genetic differentiation. On account of the multiple discriminatory markers, multilocus enzyme electrophoresis typing seems to be a very powerful tool for epidemiological and reproductive mode studies of A. fumigatus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.