ReviewEnvironmental health perspectives1996
Research needs for the risk assessment of health and environmental effects of endocrine disruptors: a report of the U.S. EPA-sponsored workshop.
Review in Environmental health perspectives, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 197 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
197 citing papers in PubMed, 3 syntheses or guidelines pooled it, 1,124 citations in OpenAlex.
- Applying a modified systematic review and integrated assessment framework (SYRINA) - a case study on triphenyl phosphate.Environmental science. Processes & impacts · 2024Pooled it
- A proposed framework for the systematic review and integrated assessment (SYRINA) of endocrine disrupting chemicals.Environmental health : a global access science source · 2016Pooled it
- Using systematic reviews for hazard and risk assessment of endocrine disrupting chemicals.Reviews in endocrine & metabolic disorders · 2015Pooled it
- Bridging exposure and disease: serum hormones as potential mediators between PBDEs and preeclampsia.BMC pregnancy and childbirth · 2026Article
- The Improper Disposal of Drugs and the Lack of Information About It Among a Highly Educated Population in Brazil: Analysis of the Factors Influencing Correct Disposal.Pharmacy (Basel, Switzerland) · 2026Article
- Biomonitoring: a demonstration of the importance of direct analytical methods for the assessment of chemical exposures.Frontiers in chemistry · 2026Article
- Evaluation of Biocontrol Efficacy ofMicroorganisms · 2025Article
- The Plasticizer Dibutyl Phthalate (DBP) Impairs Pregnancy Vascular Health: Insights into Calcium Signaling and Nitric Oxide Involvement.Journal of xenobiotics · 2025Article
- A State of the Science Review of Human Health Effects of the Michigan Polybrominated Biphenyl Contamination after Five Decades.Environmental health perspectives · 2025Review
- Extraction, quantification and health risk assessment of bisphenol A from various kinds of packaged milk and baby bottles.Food chemistry: X · 2025Article
- Nanoplastics as Gene and Epigenetic Modulators of Endocrine Functions: A Perspective.International journal of molecular sciences · 2025Review
- Impact of 17-alpha ethinyl estradiol (EE2) and diethyl phthalate (DEP) exposure on microRNAs expression and their target genes in differentiated SH-SY5Y cells.Scientific reports · 2025Article
- Pesticides and public health: discussing risks in Brazilian agro-industrial growth.Frontiers in toxicology · 2025Article
- Endocrine disruptors, obesity, and metabolic syndrome.Turkish journal of medical sciences · 2025Review
- Potential effects of environmental toxicants on sperm quality and potential risk for fertility in humans.Frontiers in endocrinology · 2025Review
- In vitro exposure to butylparaben impairs the integrity and size of ovarian follicles in a bovine model.Veterinary research communications · 2024Article
- Drug-degrading bacteria isolated from the effluent water of a sewage plant.Biologia futura · 2024Article
- A Pretty Kettle of Fish: A Review on the Current Challenges in Mediterranean Teleost Reproduction.Animals : an open access journal from MDPI · 2024Review
- Comparing Transcriptomic Points of Departure to Apical Effect Concentrations For Larval Fathead Minnow Exposed to Chemicals with Four Different Modes Of Action.Archives of environmental contamination and toxicology · 2024Article
- A System Biology Approach Reveals New Targets for Human Thyroid Gland Toxicity in Embryos and Adult Individuals.Metabolites · 2024Article
137 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The hypothesis has been put forward that humans and wildlife species adverse suffered adverse health effects after exposure to endocrine-disrupting chemicals. Reported adverse effects include declines in populations, increases in cancers, and reduced reproductive function. The U.S. Environmental Protection Agency sponsored a workshop in April 1995 to bring together interested parties in an effort to identify research gaps related to this hypothesis and to establish priorities for future research activities. Approximately 90 invited participants were organized into work groups developed around the principal reported health effects-carcinogenesis, reproductive toxicity, neurotoxicity, and immunotoxicity-as well as along the risk assessment paradigm-hazard identification, dose-response assessment, exposure assessment, and risk characterization. Attention focused on both ecological and human health effects. In general, group felt that the hypothesis warranted a concerted research effort to evaluate its validity and that research should focus primarily on effects on development of reproductive capability, on improved exposure assessment, and on the effects of mixtures. This report summarizes the discussions of the work groups and details the recommendations for additional research.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.