ArticleClinical and diagnostic laboratory immunology1996
Clonal diversity of Streptococcus mitis biovar 1 isolates from the oral cavity of human neonates.
Article in Clinical and diagnostic laboratory immunology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Clinical and microbiological responses of volunteers to combined intranasal and oral inoculation with a Streptococcus gordonii carrier strain intended for future use as a group A streptococcus vaccine.Infection and immunity · 2005Trial
- Population genomics of Streptococcus mitis in UK and Ireland bloodstream infection and infective endocarditis cases.Nature communications · 2024Article
- Novel Multilocus Sequence Typing and Global Sequence Clustering Schemes for Characterizing the Population Diversity of Streptococcus mitis.Journal of clinical microbiology · 2023Article
- Spatial Distribution and Chemical Tolerance of Streptococcus mutans within Dual-Species Cariogenic Biofilms.Microbes and environments · 2018Article
- Commensal Streptococcus mitis is a unique vector for oral mucosal vaccination.Microbes and infection · 2015Article
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- Isolation and identification of bifidobacteriaceae from human saliva.Applied and environmental microbiology · 2008Article
- Population diversity and dynamics of Streptococcus mitis, Streptococcus oralis, and Streptococcus infantis in the upper respiratory tracts of adults, determined by a nonculture strategy.Infection and immunity · 2008Article
- Antibody binding to Streptococcus mitis and Streptococcus oralis cell fractions.Archives of oral biology · 2008Article
- Extent of horizontal gene transfer in evolution of Streptococci of the salivarius group.Journal of bacteriology · 2007Article
- Physiological and serological variation in Streptococcus mitis biovar 1 from the human oral cavity during the first year of life.Archives of oral biology · 2007Article
- Clonal diversity and turnover of Streptococcus mitis bv. 1 on shedding and nonshedding oral surfaces of human infants during the first year of life.Clinical and diagnostic laboratory immunology · 2005Article
- Discrimination of Streptococcus pneumoniae from viridans group streptococci by genomic subtractive hybridization.Journal of clinical microbiology · 2005Article
- Study of humoral immunity to commensal oral bacteria in human infants demonstrates the presence of secretory immunoglobulin A antibodies reactive with Actinomyces naeslundii genospecies 1 and 2 ribotypes.Clinical and diagnostic laboratory immunology · 2004Article
- Effect of the environment on genotypic diversity of Actinomyces naeslundii and Streptococcus oralis in the oral biofilm.Applied and environmental microbiology · 2003Article
- Population dynamics of Streptococcus mitis in its natural habitat.Infection and immunity · 2001Article
- Genotypic heterogeneity of Streptococcus oralis and distinct aciduric subpopulations in human dental plaque.Applied and environmental microbiology · 2000Article
- Macrorestriction fingerprinting of "Streptococcus milleri" group bacteria by pulsed-field gel electrophoresis.Journal of clinical microbiology · 2000Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
The clonal diversity of 101 isolates of the pioneer bacterium Streptococcus mitis biovar 1 obtained from the oral cavities of 40 human neonates 1 to 3 days, 2 weeks, and 1 month postpartum was examined by using rRNA gene restriction patterns. There was a high degree of genetic diversity, with the 101 isolates comprising 93 unique PvuII ribotypes. There were eight identical pairs of ribotype patterns, and seven of the eight pairs were obtained from individual neonates. Only one identical pair comprised isolates obtained from different neonates. In all but two cases, isolates with matching ribotypes were obtained at one visit. Two pairs of isolates with matching ribotype patterns were obtained from neonates on successive visits. The ribotype patterns of the isolates were examined by cluster analysis. The isolates forming each cluster were very similar, yet each cluster was well separated from its neighbors. When several isolates were obtained from individual neonates at a particular visit, in some instances they were contained in a single cluster, whereas in other cases each isolate was contained in a separate cluster. Isolates obtained from individual neonates on successive visits tended to be contained in different clusters. This high degree of diversity, which has been observed in other mucosal commensal bacteria, may serve as a mechanism for avoiding immune elimination of these bacteria.
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