ArticleMammalian genome : official journal of the International Mammalian Genome Society1996
A new mouse mutation causing male sterility and histoincompatibility.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- The mouse curly whiskers (Molecular genetics and metabolism reports · 2019Article
- The male sterility and histoincompatibility (mshi) mutation in mice is a natural variant of microtubule-associated protein 7 (Mtap7).Molecular genetics and metabolism · 2009Article
- Male germ cells require polyenoic sphingolipids with complex glycosylation for completion of meiosis: a link to ceramide synthase-3.The Journal of biological chemistry · 2008Article
- Gene expression study in the juvenile mouse testis: identification of stage-specific molecular pathways during spermatogenesis.Mammalian genome : official journal of the International Mammalian Genome Society · 2006Article
- A missense mutation in the mouse Col2a1 gene causes spondyloepiphyseal dysplasia congenita, hearing loss, and retinoschisis.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2003Article
- Hearing loss associated with the modifier of deaf waddler (mdfw) locus corresponds with age-related hearing loss in 12 inbred strains of mice.Hearing research · 2001Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Male sterility and histoincompatibility, mshi, is an autosomal recessive mutation in BALB/cBy mice that causes reduced testis size and sterility in homozygous males. The testes of homozygous mutants are highly disorganized and appear to have a block in the regulation of male germ cell proliferation. No heterozygous effect is detectable. Reproduction is unaffected in females carrying the mutation. The mutation also affects histocompatibility; most homozygous males and females reject sex-matched skin grafts from BALB/cBy mice. We used an intercross between BALB/cBy and CAST/Ei to map the mshi mutation to the proximal end of Chromosome (Chr) 10. The most likely gene order places the mutation between D10Mit80 and D10Mit16, near the interferon gamma receptor locus, Ifgr, which may be a candidate gene for this mutation.
Indexed as
Identifiers
8875885What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.