Evidence map›Paper›PMID 8873376›Full record

ReviewUrological research1996

Oxalate transport and calcium oxalate renal stone disease.

C F Verkoelen, J C Romijn

Abstract readEditorialReview
PubMed Publisher
In one paragraph

Review in Urological research, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Enhanced gastrointestinal passive paracellular permeability contributes to the obesity-associated hyperoxaluria.American journal of physiology. Gastrointestinal and liver physiology · 2019
    Article
  3. Article
  4. Review
  5. Article
  6. Cholinergic signaling inhibits oxalate transport by human intestinal T84 cells.American journal of physiology. Cell physiology · 2012
    Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Cell cultures and nephrolithiasis.World journal of urology · 1997
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

C F Verkoelen
J C Romijn

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperoxaluria is considered to play a crucial role in calcium oxalate (CaOx) renal stone disease. The amount of oxalate excreted into the urine depends on intestinal absorption, endogenous production, renal clearance and renal tubular transport. Since a primary disorder has not been found so far in most CaOx stone formers and since oxalate is freely filtered at the glomerulus, most studies are presently focussed on alterations in epithelial oxalate transport pathways. Oxalate can be transported across an epithelium by the paracellular (passive) and transcellular (active) pathway. Oxalate transport across cellular membranes is mediated by anion-exchange transport proteins. A defect in the structure of these transport proteins could explain augmented transcellular oxalate transport. Little is known about the physiological regulation of oxalate transport. In this review cellular transport systems for oxalate will be summarized with special attention for the progress that has been made to study oxalate transport in a model of cultured renal tubule cells. Better understanding of the physiological processes that are involved in oxalate transport could yield information on the basis of which it might be possible to design new approaches for an effective treatment of CaOx stone disease.

Indexed as

AnimalsBiological TransportCalcium OxalateHumansIntestinal MucosaKidneyKidney CalculiMethodsOxalatesSodium ChlorideCalcium OxalateOxalatesSodium Chloride

Identifiers

PMID8873376

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.