Evidence map›Paper›PMID 8869717›Full record

ArticleActa neurochirurgica1996

The role of angiogenic factor bFGF in the development of dural AVFs.

T Terada, M Tsuura, N Komai, R T Higashida, V V Halbach, C F Dowd, C B Wilson, G B Hieshima

Abstract read
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In one paragraph

Article in Acta neurochirurgica, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Pathophysiology and classification of intracranial and spinal dural AVF.Journal of cerebrovascular and endovascular neurosurgery · 2022
    Article
  3. Article
  4. Surgical neurology international · 2022
    Article
  5. Review
  6. Article
  7. Cavernous Sinus Dural Arteriovenous Fistulas: General Aspects.Journal of neuroendovascular therapy · 2020
    Review
  8. Review
  9. Article
  10. Mechanism of the formation of dural arteriovenous fistula: the role of the emissary vein.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2011
    Article
  11. Development of indirect cavernous dural arteriovenous fistula after trapping for direct carotid cavernous fistula. A case report.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2011
    Article
  12. Article
  13. Article
  14. Multiple dural arteriovenous fistulas. Radiologic progression and endovascular cure. Case report.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2002
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

T TeradaDepartment of Neurological Surgery, Wakayama Medical College, Japan.
M Tsuura
N Komai
R T Higashida
V V Halbach
C F Dowd
C B Wilson
G B Hieshima
Neurological Surgery · USWakayama Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDural arteriovenous fistulas (dAVFs) are known to be acquired disorders. Angiogenic stimulants, such as basic fibroblast growth factor (bFGF), may be involved in the evolution of this disorder. We examined the appearance and localization of bFGF, in human dAVF sinuses, versus a control using immunohistochemical techniques, to evaluate these qualitative differences. PATIENTS AND

methodsFour human dural sinuses from dAVF patients, and one control dural sinus were removed at surgery or autopsy and used for this study. Immunohistochemistry for bFGF was performed in all five specimens to identify its appearance and localization. Immunohistochemistry for alpha smooth muscle actin, factor VII related antigen, and macrophage (CD-68) were done in all tissues to identify the bFGF positive cell types.

resultsIn the control dural sinus, there was negative staining by bFGF immunohistochemistry. However, in all four sinuses of the dAVF patients, smooth muscle cells, endothelial cells, and meningeal cells were stained positively in various degrees by bFGF immunohistochemistry.

conclusionbFGF may be significant in the development of dAVFs, judging from its strong immunoreactivity in the sinuses of dAVF patients.

Indexed as

AdultAgedArteriovenous FistulaCerebrovascular CirculationDura MaterFemaleFibroblast Growth Factor 2HumansImmunohistochemistryMaleMiddle AgedFibroblast Growth Factor 2

Identifiers

PMID8869717
OpenAlexW2041942122

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.