Evidence map›Paper›PMID 8862516›Full record

ReviewMolecular biology of the cell1996

Proteins in unexpected locations.

N R Smalheiser

Abstract readReview
In one paragraph

Review in Molecular biology of the cell, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 86 citations in OpenAlex.

  1. mRNA Transcript Variants Expressed in Mammalian Cells.International journal of molecular sciences · 2025
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Extracellular Actin Is a Receptor forFrontiers in cellular and infection microbiology · 2018
    Article
  8. Article
  9. Article
  10. New insights into the role of angiogenin in actin polymerization.International review of cell and molecular biology · 2012
    Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Caveolae: biochemical analysis.Molecular biology reports · 2004
    Article
  17. Article
  18. Article
  19. Article
  20. Troponin I is present in human cartilage and inhibits angiogenesis.Proceedings of the National Academy of Sciences of the United States of America · 1999
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

N R SmalheiserDepartment of Pediatrics, University of Chicago, Illinois 60637, USA.
University of Illinois Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Members of all classes of proteins--cytoskeletal components, secreted growth factors, glycolytic enzymes, kinases, transcription factors, chaperones, transmembrane proteins, and extracellular matrix proteins--have been identified in cellular compartments other than their conventional sites of action. Some of these proteins are expressed as distinct compartment-specific isoforms, have novel mechanisms for intercompartmental translocation, have distinct endogenous biological actions within each compartment, and are regulated in a compartment-specific manner as a function of physiologic state. The possibility that many, if not most, proteins have distinct roles in more than one cellular compartment has implications for the evolution of cell organization and may be important for understanding pathological conditions such as Alzheimer's disease and cancer.

Indexed as

AcetylcholinesteraseActinsAnimalsApolipoproteins EBiological Transport, ActiveCytoskeletal ProteinsExtracellular Matrix ProteinsGlycolysisGlycosyltransferasesGrowth SubstancesHumansLamininModels, BiologicalPhosphotransferasesProtein FoldingProteinsAcetylcholinesteraseActinsApolipoproteins ECytoskeletal ProteinsExtracellular Matrix ProteinsGlycosyltransferasesGrowth SubstancesLamininPhosphotransferasesProteins

Identifiers

PMID8862516
PMCPMC275954
OpenAlexW2114445299

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.