ReviewHistochemistry and cell biology1996
Immunogold labelling of neuroendocrine peptides with special reference to antibody specificity and multiple staining techniques.
Review in Histochemistry and cell biology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Characterizing intercellular signaling peptides in drug addiction.Neuropharmacology · 2009Review
- The silver anniversary of gold: 25 years of the colloidal gold marker system for immunocytochemistry and histochemistry.Histochemistry and cell biology · 1996Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immunogold methods have been very important for research on the neuroendocrine system. The compatibility of immunogold probes with optimal contrasting for electron microscopy has made localizations of neuroendocrine peptides to different subtypes of secretory organelles possible and, currently, methods using covalent attachment of nanogold particles to antibodies and neuropeptide ligands hold promise for immunocytochemistry, receptor localizations and in situ hybridizations. Multihormonal phenotypes are a hallmark of both the developing and mature neuroendocrine system. The possibility to localize multiple coexisting messengers by multilabelling immunogold methods is emphasized, and different methods for achieving this are discussed. The most difficult part of immunocytochemistry involves definitions and interpretations of specificity, and a number of limitations and control procedures are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.