ArticleProceedings of the National Academy of Sciences of the United States of America1996
Rapid refolding of a proline-rich all-beta-sheet fibronectin type III module.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Design and Synthesis of Monobody Variants with Low Immunogenicity.ACS medicinal chemistry letters · 2023Article
- Replacement of the native cis prolines by alanine leads to simplification of the complex folding mechanism of a small globular protein.Biophysical journal · 2023Article
- FN3 Domain Displaying Double Epitopes: A Cost-Effective Strategy for Producing Substitute Antigens.Frontiers in molecular biosciences · 2021Article
- Structural and Evolutionary Insights within the Polysaccharide Deacetylase Gene Family ofGenes · 2018Article
- Refolding the unfoldable: A systematic approach for renaturation of Bacillus circulans xylanase.Protein science : a publication of the Protein Society · 2017Article
- Structural basis for biofilm formation via the Vibrio cholerae matrix protein RbmA.Journal of bacteriology · 2013Article
- Transient opening of fibronectin type III (FNIII) domains: the interaction of the third FNIII domain of FN with anastellin.Biochemistry · 2009Article
- Article
- Novel mutant human fibronectin FIII9-10 domain pair with increased conformational stability and biological activity.Protein engineering · 2002Article
- Conserved and nonconserved features of the folding pathway of hisactophilin, a beta-trefoil protein.Protein science : a publication of the Protein Society · 2002Article
- Probing protein conformational changes in living cells by using designer binding proteins: application to the estrogen receptor.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- Simulated refolding of stretched titin immunoglobulin domains.Biophysical journal · 2001Article
- A partially folded intermediate species of the beta-sheet protein apo-pseudoazurin is trapped during proline-limited folding.Protein science : a publication of the Protein Society · 2001Article
- Unfolding of titin domains explains the viscoelastic behavior of skeletal myofibrils.Biophysical journal · 2001Article
- Functional dissection of the major structural protein of bluetongue virus: identification of key residues within VP7 essential for capsid assembly.Journal of virology · 2000Article
- Folding of beta-sandwich proteins: three-state transition of a fibronectin type III module.Protein science : a publication of the Protein Society · 2000Article
- Mechanical and chemical unfolding of a single protein: a comparison.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- Stretching lattice models of protein folding.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- Forced unfolding of the fibronectin type III module reveals a tensile molecular recognition switch.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- How evolution makes proteins fold quickly.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fibronectin type III modules contain approximately 90 residues and are an extremely common building block of animal proteins. Despite containing a complex all-beta-sheet topology and eight prolines, the refolding of the 10th type III module of human fibronectin has been found to be very rapid, with native core packing, amide hydrogen bonding, and backbone conformation all recovered within 1 s at 5 degrees C. These observations indicate that this domain can overcome many structural characteristics often thought to slow the folding process.
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