ArticleEuropean journal of nuclear medicine1996
Age-related changes in the global skeletal uptake of technetium-99m methylene diphosphonate in healthy women.
Article in European journal of nuclear medicine, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 14 citations in OpenAlex.
- Bone metabolism assessment, bone metabolism index designation and the determination of its normal values range in young healthy women.Medical science monitor : international medical journal of experimental and clinical research · 2011Article
- Bone turnover markers are correlated with total skeletal uptake of 99mTc-methylene diphosphonate (99mTc-MDP).BMC medical physics · 2009Article
- Short-term effects of surgery in post-menopausal patients with primary hyperparathyroidism and normal bone turnover.Journal of endocrinological investigation · 2001Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A short-term evaluation of global skeletal uptake (GSU) of technetium-99m methylene diphosphonate (MDP) was performed in 40 healthy female subjects with a wide age range in order to investigate the clinical performance of the technique and to detect the age-related changes in bone turnover. The results obtained were compared with measurements of the main biochemical markers of skeletal metabolism. We found that GSU increases progressively with age, independently of concomitant changes in renal function; significant correlations with biochemical markers of bone formation were also found. Therefore, the method appears to provide useful information concerning the bone turnover rate, and is also applicable to elderly people owing to its simplicity.
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