ArticleGenetics1996
An extragenic suppressor of the mitosis-defective bimD6 mutation of Aspergillus nidulans codes for a chromosome scaffold protein.
Article in Genetics, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 50 citations in OpenAlex.
- Rio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores.Nature communications · 2023Article
- Comparative profiling of canonical and non-canonical small RNAs in the rice blast fungus,Frontiers in microbiology · 2022Article
- The Rio1 protein kinases/ATPases: conserved regulators of growth, division, and genomic stability.Current genetics · 2019Review
- Discovery of McrA, a master regulator of Aspergillus secondary metabolism.Molecular microbiology · 2017Article
- Characterization of the mutagenic spectrum of 4-nitroquinoline 1-oxide (4-NQO) in Aspergillus nidulans by whole genome sequencing.G3 (Bethesda, Md.) · 2014Article
- Factors required for activation of urease as a virulence determinant in Cryptococcus neoformans.mBio · 2013Article
- Functional analysis of the Aspergillus nidulans kinome.PloS one · 2013Article
- Genome-wide transcriptional profiling of appressorium development by the rice blast fungus Magnaporthe oryzae.PLoS pathogens · 2012Article
- Late cytoplasmic maturation of the small ribosomal subunit requires RIO proteins in Saccharomyces cerevisiae.Molecular and cellular biology · 2003Article
- Establishment and maintenance of sister chromatid cohesion in fission yeast by a unique mechanism.The EMBO journal · 2001Article
- Processing of 20S pre-rRNA to 18S ribosomal RNA in yeast requires Rrp10p, an essential non-ribosomal cytoplasmic protein.The EMBO journal · 2001Article
- BimD/SPO76 is at the interface of cell cycle progression, chromosome morphogenesis, and recombination.Proceedings of the National Academy of Sciences of the United States of America · 2001Article
- Extragenic suppressors of the nimX2(cdc2) mutation of Aspergillus nidulans affect nuclear division, septation and conidiation.Genetics · 2000Article
- Characterization of vertebrate cohesin complexes and their regulation in prophase.The Journal of cell biology · 2000Article
- Characterization of fission yeast cohesin: essential anaphase proteolysis of Rad21 phosphorylated in the S phase.Genes & development · 2000Article
- Pds5p is an essential chromosomal protein required for both sister chromatid cohesion and condensation in Saccharomyces cerevisiae.The Journal of cell biology · 2000Article
- HEAT repeats associated with condensins, cohesins, and other complexes involved in chromosome-related functions.Genome research · 2000Article
- Identification of Xenopus SMC protein complexes required for sister chromatid cohesion.Genes & development · 1998Article
- Human autoantibodies reveal titin as a chromosomal protein.The Journal of cell biology · 1998Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We previously identified a gene, bimD, that functions in chromosome segregation and contains sequences suggesting that it may be a DNA-binding protein. Two conditionally lethal mutations in bimD arrest with aberrant mitotic spindles at restrictive temperature. These spindles have one-third the normal number of microtubules, and the chromosomes never attach to the remaining microtubules. For this reason, we hypothesized that BIMD functioned in chromosome segregation, possibly as a component of the kinetochore. To identify other components that function with bimD, we conducted a screen for extragenic suppressors of the bimD5 and bimD6 mutations. We have isolated seven cold-sensitive extragenic suppressors of bimD6 heat sensitivity that represent three or possibly four separate sud genes. We have cloned one of the suppressor genes by complementation of the cold-sensitive phenotype of the sudA3 mutation. SUDA belongs to the DA-box protein family. DA-box proteins have been shown to function in chromosome structure and segregation. Thus bimD and the sud genes cooperatively function in chromosome segregation in Aspergillus nidulans.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.