ReviewJournal of bioenergetics and biomembranes1996
The role of gap junction membrane channels in secretion and hormonal action.
Review in Journal of bioenergetics and biomembranes, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 78 citations in OpenAlex.
- A Lack of GD3 Synthase Leads to Impaired Renal Expression of Connexins and Pannexin1 inInternational journal of molecular sciences · 2022Article
- The Pancreatic β-Cell: The Perfect Redox System.Antioxidants (Basel, Switzerland) · 2021Review
- Flutamide induces alterations in the cell-cell junction ultrastructure and reduces the expression of Cx43 at the blood-testis barrier with no disturbance in the rat seminiferous tubule morphology.Reproductive biology and endocrinology : RB&E · 2016Article
- A low-protein diet during pregnancy prevents modifications in intercellular communication proteins in rat islets.Biological research · 2015Article
- Molecular basis for the regulation of islet beta cell mass in mice: the role of E-cadherin.Diabetologia · 2013Article
- Protein-mediated interactions of pancreatic islet cells.Scientifica · 2013Review
- Molecular mechanism of pancreatic and salivary gland fluid and HCO3 secretion.Physiological reviews · 2012Review
- Connexins and the kidney.American journal of physiology. Regulatory, integrative and comparative physiology · 2010Review
- The hyperbolic effect of density and strength of inter beta-cell coupling on islet bursting: a theoretical investigation.Theoretical biology & medical modelling · 2008Article
- Functional remodeling of gap junction-mediated electrical communication between adrenal chromaffin cells in stressed rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2008Article
- Revascularization and remodelling of pancreatic islets grafted under the kidney capsule.Journal of anatomy · 2007Article
- Morphological changes of isolated rat pancreatic islets: a structural, ultrastructural and morphometric study.Journal of anatomy · 2006Article
- The Ca2+ dynamics of isolated mouse beta-cells and islets: implications for mathematical models.Biophysical journal · 2003Article
- Gap junctions mediate electrical signaling and ensuing cytosolic Ca2+ increases between chromaffin cells in adrenal slices: A role in catecholamine release.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2001Article
- Junctional communication of pancreatic beta cells contributes to the control of insulin secretion and glucose tolerance.The Journal of clinical investigation · 2000Article
- Defective regulation of gap junctional coupling in cystic fibrosis pancreatic duct cells.The Journal of clinical investigation · 1999Article
- Connexin43 PDZ2 binding domain mutants create functional gap junctions and exhibit altered phosphorylation.Cell communication & adhesionArticle
- Gap junctional communication in morphogenesis.Progress in biophysics and molecular biologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Connexins, gap junctions, and coupling are obligatory features of both endocrine and exocrine glandular epithelia. Evidence from these two types of tissues, and particularly from pancreatic islets and acini, indicates that cell-to-cell communication via gap junction channels is required for proper biosynthesis, storage, and release of specific secretory products. However, endocrine and exocrine glands express a different set of connexins and show opposite connexin and coupling changes in relation with the activation and inhibition of their secretory function. Also, several hormones modulate connexin and coupling expression, and junctional coupling affects hormonal stimulation. These observations indicate that gap junction channels play an important role in the control of secretion and hormonal action.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.