ReviewJournal of bioenergetics and biomembranes1996
Multiple connexin proteins in single intercellular channels: connexin compatibility and functional consequences.
Review in Journal of bioenergetics and biomembranes, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
54 citing papers in PubMed, 190 citations in OpenAlex.
- Connexins in epidermal health and diseases: insights into their mutations, implications, and therapeutic solutions.Frontiers in physiology · 2024Review
- Article
- Article
- Comparing astrocytic gap junction of genetic absence epileptic rats with control rats: an experimental study.Brain structure & function · 2021Article
- Ceramide/protein phosphatase 2A axis is engaged in gap junction impairment elicited by PCB153 in liver stem-like progenitor cells.Molecular and cellular biochemistry · 2021Article
- Gap Junctions in the Bone Marrow Lympho-Hematopoietic Stem Cell Niche, Leukemia Progression, and Chemoresistance.International journal of molecular sciences · 2020Review
- Binding of α-synuclein oligomers to Cx32 facilitates protein uptake and transfer in neurons and oligodendrocytes.Acta neuropathologica · 2019Article
- Structure and Function of Cochlear Gap Junctions and Implications for the Translation of Cochlear Gene Therapies.Frontiers in cellular neuroscience · 2019Article
- Therapeutic strategies targeting connexins.Nature reviews. Drug discovery · 2018Review
- Connexin-Mediated Functional and Metabolic Coupling Between Astrocytes and Neurons.Frontiers in molecular neuroscience · 2018Article
- Glycocalyx in Atherosclerosis-Relevant Endothelium Function and as a Therapeutic Target.Current atherosclerosis reports · 2017Review
- A structural and functional comparison of gap junction channels composed of connexins and innexins.Developmental neurobiology · 2017Review
- Connexins in the Central Nervous System: Physiological Traits and Neuroprotective Targets.Frontiers in physiology · 2017Review
- Erythrokeratodermia variabilis et progressiva allelic to oculo-dento-digital dysplasia.The Journal of investigative dermatology · 2015Article
- The role of the C-terminus in functional expression and internalization of rat connexin46 (rCx46).Journal of bioenergetics and biomembranes · 2013Article
- Connexin diversity in the heart: insights from transgenic mouse models.Frontiers in pharmacology · 2013Article
- GJB2 Gene Mutations in Syndromic Skin Diseases with Sensorineural Hearing Loss.Current genomics · 2011Article
- Connexin26 expression in brain parenchymal cells demonstrated by targeted connexin ablation in transgenic mice.The European journal of neuroscience · 2011Article
- Dominant Cx26 mutants associated with hearing loss have dominant-negative effects on wild type Cx26.Molecular and cellular neurosciences · 2011Article
- Regulation of cellular function by connexin hemichannels.International journal of biochemistry and molecular biology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In vertebrates, the protein subunits of intercellular channels found in gap junctions are encoded by a family of genes called connexins. These channels span two plasma membranes and result from the association of two half channels, or connexons, which are hexameric assemblies of connexins. Physiological analysis of channel formation and gating has revealed unique patterns of connexin-connexin interaction, and uncovered novel functional characteristics of channels containing more than one type of connexin protein. Structure-function studies have further demonstrated that unique domains within connexins participate in the regulation of different functional properties of intercellular channels. Thus, gap junctional channels can contain more than one connexin, and this structural heterogeneity has functional consequences in vitro. Moreover, emerging evidence for the existence of intercellular channels containing multiple connexins in native tissues suggests that the functional diversity generated by connexin-connexin interaction could contribute to complex communication patterns that have been observed in vivo.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.