Evidence map›Paper›PMID 8842492›Full record

ReviewCancer metastasis reviews1996

Tumor angiogenesis: a physiological process or genetically determined?

P A D'Amore, D T Shima

Abstract readReview
PubMed Publisher
In one paragraph

Review in Cancer metastasis reviews, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. VEGF and metalloproteinase 2 (MMP 2) expression in gastric cancer tissue.Medical science monitor : international medical journal of experimental and clinical research · 2012
    Article
  3. Article
  4. Article
  5. Article
  6. Establishing a link between oncogenes and tumor angiogenesis.Molecular medicine (Cambridge, Mass.) · 1998
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

P A D'AmoreLaboratory for Surgical Research, Children's Hospital, Boston, MA 02115, USA.
D T Shima
Boston Children's Hospital · USThe Honourable Society of Lincoln's Inn · GB

Funding

TUMOR DORMANCY INDUCED BY BLOCKED ANGIOGENESISP01CA045548 · NCI · CHILDREN'S HOSPITAL BOSTON · PI KLAGSBRUN, MICHAEL · 1987 to 2011
$22.6M
NCI NIH HHS CA45548NEI NIH HHS EY05985
6 · The paper itself

Abstract

Continued tumor growth is dependent upon the growth of new blood vessels. This commentary reviews the mechanisms whereby tumors become vascularized and examines whether tumor angiogenesis is solely an example of a normal physiologic process or is part of the genetic program of the tumor. The likelihood that neovascularization of tumors combines both of these components, that is, utilizing tumor-specific elements as well as capacities common to all cells, is discussed.

Indexed as

AnimalsHumansNeoplasmsNeovascularization, Pathologic

Identifiers

PMID8842492
OpenAlexW2093136043

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.