Evidence map›Paper›PMID 8839784›Full record

ReviewImmunologic research1996

Extracellular matrix and lung inflammation.

J Roman

Abstract readReview
PubMed Publisher
In one paragraph

Review in Immunologic research, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 75 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Plasminogen Activator Inhibitor-1 Is Critical in Alcohol-Enhanced Acute Lung Injury in Mice.American journal of respiratory cell and molecular biology · 2017
    Article
  5. Article
  6. Predisposition for disrepair in the aged lung.The American journal of the medical sciences · 2012
    Article
  7. Article
  8. Article
  9. Article
  10. Extracellular matrix influences alveolar epithelial claudin expression and barrier function.American journal of respiratory cell and molecular biology · 2010
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

J RomanDepartment of Medicine, Atlanta Veterans Affairs Medical Center, GA 30033, USA.
Atlanta VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung injury triggers an acute inflammatory response characterized by increased expression and deposition of extracellular matrix (ECM) components such as fibronectin and collagen. Although the function of newly deposited matrices in injured lungs is unknown, their ability to affect the migration, proliferation, differentiation, and activation state of cells in vitro suggests an important role in the initiation and maintenance of the inflammatory response in vivo. Interactions between immune and nonimmune cells with the lung ECM are mediated via cell surface receptors of the integrin family which link the ECM with intracellular molecules involved in signal transduction. Activation of integrin-mediated intracellular signals may promote inflammation by facilitating leukocyte recruitment and cytokine expression.

Indexed as

AnimalsExtracellular Matrix ProteinsHumansInflammationLungExtracellular Matrix Proteins

Identifiers

PMID8839784
OpenAlexW2034548191

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.