ArticleHuman genetics1996
A solitary human H3 histone gene on chromosome 1.
Article in Human genetics, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- The eutherian-specific histone H3.4 promotes germ cell development and reproductive fitness.Nature communications · 2026Article
- A standardized nomenclature for mammalian histone genes.Epigenetics & chromatin · 2022Review
- Histone variants: The unsung guardians of the genome.DNA repair · 2022Review
- Interactions With Histone H3 & Tools to Study Them.Frontiers in cell and developmental biology · 2020Review
- Identification of the amino acid residues responsible for stable nucleosome formation by histone H3.Y.Nucleus (Austin, Tex.) · 2017Article
- Structure and function of human histone H3.Y nucleosome.Nucleic acids research · 2016Article
- Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis.Epigenetics & chromatin · 2016Article
- Structural basis of a nucleosome containing histone H2A.B/H2A.Bbd that transiently associates with reorganized chromatin.Scientific reports · 2013Article
- A unified phylogeny-based nomenclature for histone variants.Epigenetics & chromatin · 2012Article
- Chromatin remodelling initiation during human spermiogenesis.Biology open · 2012Article
- Specialized compartments of cardiac nuclei exhibit distinct proteomic anatomy.Molecular & cellular proteomics : MCP · 2011Article
- Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Nucleosome formation with the testis-specific histone H3 variant, H3t, by human nucleosome assembly proteins in vitro.Nucleic acids research · 2008Article
- Histone H3 variants in male gametic cells of lily and H3 methylation in mature pollen.Plant molecular biology · 2006Article
- Histone structure and nucleosome stability.Expert review of proteomics · 2005Review
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A solitary histone H3 gene encoding a novel H3 protein sequence has been isolated. This H3 gene maps to chromosome 1 (1q42), whereas we have shown previously that the majority of the human histone genes form a large cluster on chromosome 6 (6p21.3). In addition, a small cluster has been described at 1q21. The clustered histone genes are expressed during the S-phase of the cell cycle, hence their definition as replication-dependent histone genes. In contrast, expression of replacement histone genes is essentially cell-cycle independent; they are solitary genes and map outside the major clusters. The newly described H3 gene maps outside all known histone gene clusters and varies by four amino acid residues from the consensus mammalian H3 structure. In contrast to other solitary histone genes, this human H3 gene shows the consensus promoter and 3' flanking portions that are typical for replication-dependent genes.
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