ReviewJournal of neuro-oncology
Current treatment of thalamic gliomas in children.
Review in Journal of neuro-oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 39 citations in OpenAlex.
- Surgical Approach to Thalamic Tumors.Advances and technical standards in neurosurgery · 2022Article
- Evolution of surgical attitudes to paediatric thalamic tumours: the alder hey experience.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Review
- Infiltrative gliomas of the thalamus in children: the role of surgery in the era of H3 K27M mutant midline gliomas.Acta neurochirurgica · 2021Article
- Surgical and molecular considerations in the treatment of pediatric thalamopeduncular tumors.Journal of neurosurgery. Pediatrics · 2017Article
- Distant recurrences limit the survival of patients with thalamic high-grade gliomas after successful resection.Neurosurgical review · 2017Article
- Clinical, radiological, and pathological features of 33 adult unilateral thalamic gliomas.World journal of surgical oncology · 2016Article
- Pediatric thalamic tumors in the MRI era: a Canadian perspective.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016Article
- Surgical resection of unilateral thalamic tumors in adults: approaches and outcomes.BMC neurology · 2015Article
- Thalamic tumors in children.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2014Article
- Pediatric bilateral large concurrent thalamic glioblastoma: An unusual case report.Journal of pediatric neurosciences · 2014Article
- Article
- Surgical management of tumors producing the thalamopeduncular syndrome of childhood.Journal of neurosurgery. Pediatrics · 2011Article
- Common brain tumours in children: diagnosis and treatment.Paediatric drugsReview
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Historically, the outcome of children with thalamic gliomas has been poor. Because of the potential for severe perioperative mortality, conservative approaches toward these lesions have been commonly instituted. However, recent improvements in therapeutic approaches have been numerous. These refinements have most importantly centered on improving the neurosurgical technique of tumor resection by integrating computer-assisted, stereotactic approaches. In so doing, perioperative mortality has dropped from as high as 40% to as low as 0-1%. Gross total resection confirmed with postoperative imaging is becoming an expectation. However, because of anatomical limitations or malignant histology, incomplete resections will undoubtedly occur in an effort to preserve neurological function. At the same time, not all residual disease implies a poor outcome. Indolent, low-grade gliomas of childhood are not limited to the cerebellum or optic/hypothalamic regions, and histologically similar lesions in the region of the thalamus occur with some frequency. In this case scenario, incompletely resected low-grade lesions should be followed sequentially with routine imaging; further therapy, be it surgical or adjuvant, is instituted only if disease progression is documented. Children found to have malignant gliomas of the thalamus should undergo surgical resection in an effort to relieve them of any existing mass effect. Subsequently, adjuvant therapy is utilized depending on the exact histopathology and the child's age. Thus, what evolves from recent data and current surgical techniques is an aggressively directed therapy based upon anatomical considerations and tumor type.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.