Evidence map›Paper›PMID 8828151›Full record

ReviewVirus genes1995

Retrotransposition and herpesvirus evolution.

P Brunovskis, H J Kung

Abstract readReview
PubMed Publisher
In one paragraph

Review in Virus genes, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
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  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

P BrunovskisDepartment of Molecular Biology and Microbiology, Case-Western Reserve University, Cleveland, OH 44106, USA.
H J Kung

Funding

ONCOGENE ACTIVATION IN BANDT LYMPHOMAR37CA046613 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI KUNG, HSING-JIEN · 1993 to 2000
$321k
ONCOGENE ACTIVATION IN AVIAN B &T LYMPHOMAR01CA046613 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI KUNG, HSING-JIEN · 1988 to 1992
–
NCI NIH HHS CA 46613
6 · The paper itself

Abstract

One of the more interesting developments in herpesvirus evolution concerns the acquisition of novel, non-ubiquitous herpesvirus genes. A number of these are related to known cellular genes. How did herpesviruses acquire such genes? Our recent demonstration of retrovirus integration into herpesviruses suggests a potentially important role for retrotransposition in herpesvirus evolution and in the acquisition of novel genes, cellular in origin. Herpesvirus genome development has been characterized by a number of structural and evolutionary properties that support this proposal. We first discuss the evidence for retroviral integration into herpesviruses. The functional significance of this phenomenon is presently unclear. However, in the broader context of retrotransposition, a number of attractive features serve to explain the capture of structural and regulatory elements throughout herpesvirus evolution. These possibilities are discussed in detail.

Indexed as

Evolution, MolecularRetroelementsAnimalsGene Transfer TechniquesHerpesviridaeHumansRecombination, GeneticRetroviridaeRNA, ViralRetroelementsRNA, Viral

Identifiers

PMID8828151

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.