ReviewVirus genes1995
Evolution and biological significance of human retroelements.
Review in Virus genes, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 70 citations in OpenAlex.
- Characterization of transcriptional activation and inserted-into-gene preference of various transposable elements in the Brassica species.Molecular biology reports · 2012Article
- Different transcription activity of HERV-K LTR-containing and LTR-lacking genes of the KIAA1245/NBPF gene subfamily.Genetica · 2011Article
- Human endogenous retroviruses and multiple sclerosis: innocent bystanders or disease determinants?Biochimica et biophysica acta · 2011Review
- Retroelements and their impact on genome evolution and functioning.Cellular and molecular life sciences : CMLS · 2009Review
- Maintenance of transposon-free regions throughout vertebrate evolution.BMC genomics · 2007Article
- Article
- Article
- Ancient retroviral insertions among human populations.Journal of human genetics · 2006Article
- Article
- Comprehensive analysis of human endogenous retrovirus transcriptional activity in human tissues with a retrovirus-specific microarray.Journal of virology · 2005Article
- Detection of retroviral antisense transcripts and promoter activity of the HERV-K(C4) insertion in the MHC class III region.Immunogenetics · 2004Article
- Evolution of viruses by acquisition of genes that control nuclear functions in infected cells--an introduction.Virus genes · 2002Article
- A sequence-based integrated map of chromosome 22.Genome research · 2001Article
- Evolution of viruses by acquisition of cellular RNA or DNA nucleotide sequences and genes: an introduction.Virus genes · 2000Review
- Proviral structure, chromosomal location, and expression of HERV-K-T47D, a novel human endogenous retrovirus derived from T47D particles.Journal of virology · 1998Article
- Yeast Ty1 retrotransposition is stimulated by a synergistic interaction between mutations in chromatin assembly factor I and histone regulatory proteins.Molecular and cellular biology · 1998Article
- Two groups of endogenous MMTV related retroviral env transcripts expressed in human tissues.Virus genes · 1997Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Retroelements comprise a substantial portion of the human genome. Their large number and ubiquitous distribution has led scientists to speculate about their evolutionary origin and their biological functions. Human endogenous retroviruses and their retrotransposon relatives represent a reservoir of possibly pathogenic retroviral genes that may be activated spontaneously or by environmental conditions. They can act as insertion mutagens and activate or inactivate cellular genes, or may be involved in chromosome aberrations by recombination of related elements on different chromosomal locations. Retroviral gene products themselves may also be pathogenic and, for example, could be implicated in the development of tumors and autoimmune diseases. On the other hand, endogenous retroviral elements and nonviral retroposons are thought to have played an important role in shaping the genomes of vertebrates by intracellular transposition events and by generating hot spots of recombination. In the course of time, some of these elements have acquired cellular functions, such as, for instance, in the regulation of gene expression. Therefore, the role of human endogenous retroviruses and retroposons in biological processes is currently a subject of great interest.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.