Evidence map›Paper›PMID 8827711›Full record

ReviewMolecular medicine (Cambridge, Mass.)1996

SOX genes: architects of development.

H M Prior, M A Walter

Open access · bronzeAbstract readReview
In one paragraph

Review in Molecular medicine (Cambridge, Mass.), 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 103 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Emerging Role of SOX Proteins in Breast Cancer Development and Maintenance.Journal of mammary gland biology and neoplasia · 2019
    Review
  15. Article
  16. Article
  17. Sox11 Balances Dendritic Morphogenesis with Neuronal Migration in the Developing Cerebral Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

H M PriorOcular Genetics Research Group, University of Alberta, Edmonton, Canada.
M A Walter
University of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Development in higher organisms involves complex genetic regulation at the molecular level. The emerging picture of development control includes several families of master regulatory genes which can affect the expression of down-stream target genes in developmental cascade pathways. One new family of such development regulators is the SOX gene family. The SOX genes are named for a shared motif called the SRY box a region homologous to the DNA-binding domain of SRY, the mammalian sex determining gene. Like SRY, SOX genes play important roles in chordate development. At least a dozen human SOX genes have been identified and partially characterized (Tables 1 and 2). Mutations in SOX9 have recently been linked to campomelic dysplasia and autosomal sex reversal, and other SOX genes may also be associated with human disease.

Indexed as

Genes, HomeoboxAmino Acid SequenceAnimalsChromosome MappingDNA-Binding ProteinsGene Expression RegulationHigh Mobility Group ProteinsHumansMolecular Sequence DataNuclear ProteinsSex Determination AnalysisSex-Determining Region Y ProteinSOXB1 Transcription FactorsSOXC Transcription FactorsSOXD Transcription FactorsTranscription FactorsDNA-Binding ProteinsHigh Mobility Group ProteinsNuclear ProteinsSex-Determining Region Y ProteinSOX11 protein, humanSox11 protein, mouseSOX3 protein, humanSox3 protein, mouseSOX5 protein, humanSOX6 protein, humanSOXB1 Transcription FactorsSOXC Transcription FactorsSOXD Transcription FactorsSRY protein, humanTranscription Factors

Identifiers

PMID8827711
PMCPMC2230175
OpenAlexW1858567034

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.