Evidence map›Paper›PMID 8818938›Full record

ArticleJournal of medical genetics1996

Attitudes towards bipolar disorder and predictive genetic testing among patients and providers.

L B Smith, B Sapers, V I Reus, N B Freimer

Open access · bronzeAbstract read
In one paragraph

Article in Journal of medical genetics, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
10.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 75 citations in OpenAlex.

  1. Article
  2. Review
  3. Attitudes toward the right to autonomous decision-making in psychiatric genetic testing: Controversial and context-dependent.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2019
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Ethics and neuropsychiatric genetics: a review of major issues.The international journal of neuropsychopharmacology · 2012
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
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  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

L B SmithDepartment of Psychiatry, University of California at San Francisco 94143-0984, USA.
B Sapers
V I Reus
N B Freimer
University of California, San Francisco · US

Funding

GENETIC &EPIDEMIOLOGIC STUDIES OF BIPOLAR DISORDERR01MH049499 · NIMH · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI FREIMER, NELSON B · 1992 to 2006
$2.9M
MOLECULAR GENETICS OF X-LINKED BIPOLAR DISORDERK21MH000916 · NIMH · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI FREIMER, NELSON B · 1991 to 1995
–
NIMH NIH HHS MH 00916NIMH NIH HHS MH 49499
6 · The paper itself

Abstract

Attitudes about bipolar disorder (manic depressive disorder) and genetic testing were investigated. Three groups of subjects were surveyed including members of a manic depressive support group, medical students, and psychiatry residents. The questionnaire was intended to elicit impressions and attitudes about bipolar disorder (BP) from mental health consumers and health care providers with varying levels of personal and professional familiarity with the disorder. Attitudes towards prenatal testing and pregnancy termination were also assessed. The intention hypothetically to terminate a pregnancy was influenced by the likelihood of developing BP a well as the projected course and severity of illness. Nearly half of the total sample would terminate pregnancy if the fetus were definitely to develop an unspecified form of bipolar disorder. Presumed severity of illness was also found to be a modifying factor in the decision, with a low percentage of subjects electing to terminate for a mild course of bipolar disorder and a majority opting for termination in the case of an extremely severe presentation. Support group members were the least likely to terminate a hypothetical pregnancy in the case of a positive prenatal test and were the most likely to desire childhood testing in the absence of preventive or treatment options. The possible implications of these findings, as well as avenues of future research, are discussed.

Indexed as

AttitudeAbortion, SpontaneousAdolescentAdultAgedBipolar DisorderDemographyDepressionFemaleGenetic TestingHealth PersonnelHumansMaleMiddle AgedPatientsPharmaceutical PreparationsPharmaceutical PreparationsEmpirical ApproachGenetics and ReproductionMental Health Therapies

Identifiers

PMID8818938
PMCPMC1050660
OpenAlexW2063104163

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.