Evidence map›Paper›PMID 8818910›Full record

ArticleJournal of clinical microbiology1996

Colorimetric susceptibility testing for Aspergillus fumigatus: comparison of menadione-augmented 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide and Alamar blue tests.

B Jahn, A Stüben, S Bhakdi

Abstract readComparative Study
In one paragraph

Article in Journal of clinical microbiology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Resazurin to determine the minimum inhibitory concentration on antifungal susceptibility assays for Fonsecaea sp. using a modified EUCAST protocol.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  2. Article
  3. Article
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  8. Review
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  12. Article
  13. The spheroplast lysis assay for yeast in microtiter plate format.Applied and environmental microbiology · 1999
    Article
  14. Aspergillus fumigatus and aspergillosis.Clinical microbiology reviews · 1999
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

B JahnInstitute of Medical Microbiology and Hygiene, Johannes Gutenberg-University, Mainz, Germany. bjahn@mzdmza.zdv.uni-mainz.de
A Stüben
S Bhakdi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two colorimetric methods that use Alamar Blue or 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) for assaying the in vitro activities of antifungal agents have been described. We report that both tests performed similarly when the antifungal activity of amphotericin B against Candida albicans was determined. However, only the MTT test generated interpretable data when Aspergillus fumigatus was used.

Indexed as

OxazinesXanthenesAmphotericin BAntifungal AgentsAspergillus fumigatusCandida albicansColoring AgentsDose-Response Relationship, DrugMicrobial Sensitivity TestsTetrazolium SaltsThiazolesAmphotericin BAntifungal AgentsColoring AgentsOxazinesresazurinTetrazolium SaltsThiazolesthiazolyl blueXanthenes

Identifiers

PMID8818910
PMCPMC229182

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.