ArticleJournal of clinical microbiology1996
Fluconazole and amphotericin B antifungal susceptibility testing by National Committee for Clinical Laboratory Standards broth macrodilution method compared with E-test and semiautomated broth microdilution test.
Article in Journal of clinical microbiology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Correlation between in vitro susceptibility determined by E test and response to therapy with amphotericin B: results from a multicenter prospective study of candidemia.Antimicrobial agents and chemotherapy · 1999Trial
- Antifungal Susceptibility ofAntibiotics (Basel, Switzerland) · 2022Article
- Metabolomic profiling for the identification of potential biomarkers involved in a laboratory azole resistance in Candida albicans.PloS one · 2018Article
- Antifungal Activity of Propolis Against Yeasts Isolated From Blood Culture: In Vitro Evaluation.Journal of clinical laboratory analysis · 2016Article
- Comparative Analysis of Disc Diffusion and E-test with Broth Micro-dilution for Susceptibility Testing of Clinical Candida Isolates Against Amphotericin B, Fluconazole, Voriconazole and Caspofungin.Journal of clinical and diagnostic research : JCDR · 2015Article
- Catheter-associated urinary tract infections in intensive care units at a university hospital in Turkey.Bosnian journal of basic medical sciences · 2014Article
- Amphotericin B delivery from bone cement increases with porosity but strength decreases.Clinical orthopaedics and related research · 2011Article
- A screening assay based on host-pathogen interaction models identifies a set of novel antifungal benzimidazole derivatives.Antimicrobial agents and chemotherapy · 2011Article
- Preclinical assessment of the efficacy of mycograb, a human recombinant antibody against fungal HSP90.Antimicrobial agents and chemotherapy · 2003Article
- Correlation between E-test, disk diffusion, and microdilution methods for antifungal susceptibility testing of fluconazole and voriconazole.Antimicrobial agents and chemotherapy · 2003Article
- Susceptibility testing of fluconazole by the NCCLS broth macrodilution method, E-test, and disk diffusion for application in the routine laboratory.Journal of clinical microbiology · 2002Article
- Trends in antifungal susceptibility among Swedish Candida species bloodstream isolates from 1994 to 1998: comparison of the E-test and the Sensititre YeastOne Colorimetric Antifungal Panel with the NCCLS M27-A reference method.Journal of clinical microbiology · 2001Article
- In vivo activity of amphotericin B lipid complex in immunocompromised mice against fluconazole-resistant or fluconazole-susceptible Candida tropicalis.Antimicrobial agents and chemotherapy · 2000Article
- Applications of flow cytometry to clinical microbiology.Clinical microbiology reviews · 2000Review
- Antifungal susceptibility testing of yeast isolates from blood cultures by microbroth dilution and the E test.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 1997Article
- Evaluation of the E test for fluconazole susceptibility testing of Candida albicans isolates from oropharyngeal candidiasis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 1997Article
- Rapid susceptibility testing of Candida albicans by flow cytometry.Journal of clinical microbiology · 1997Article
- Fluconazole and amphotericin B antifungal susceptibility testing by National Committee for Clinical Laboratory Standards broth macrodilution method compared with E-test and semiautomated broth microdilution test.Journal of clinical microbiology · 1997Article
- In vitro activity of antimycotic agents determined by E-test method against vaginal Candida species.MycopathologiaArticle
Corrections and comments
- Commented on by
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A comparative study of fluconazole and amphotericin B susceptibility testing was performed with 68 clinical Candida species isolates and three test methods. The methods used were an agar diffusion method (E-test) and two broth dilution methods, the National Committee for Clinical Laboratory Standards (NCCLS) reference broth macrodilution method and an in-house-prepared semiautomated broth microdilution method based on the Bioscreen turbidometer. In the microdilution method, growth of the yeasts was measured continuously by the automatic turbidometer (Bioscreen), which permitted precise and objective determination of endpoints. MIC endpoints were read after 24 h for the microdilution method and the E-test. Amphotericin B susceptibility testing with the NCCLS method and the E-test yielded comparable results in 89% of the tests, meaning that the endpoints obtained were identical or differed by no more than 2 twofold dilutions. The NCCLS and broth microdilution tests scored 97% comparable results, and the E-test and the broth microdilution test yielded 90% comparable results. Fluconazole susceptibility testing produced 96% comparable results with the NCCLS test and the E-test, 100% comparable results with the NCCLS and the microdilution methods, and 98.5% comparable results with the microdilution method and the E-test. We conclude that the E-test and the Bioscreen microdilution method are valuable alternatives to the NCCLS reference method for routine susceptibility testing of Candida species with fluconazole and amphotericin B.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.