ReviewAnatomy and embryology1996
Colocalization of amino acid signal molecules in neurons and endocrine cells.
Review in Anatomy and embryology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 7 citations in OpenAlex.
- Identification of neurotransmitters and co-localization of transmitters in brainstem respiratory neurons.Respiratory physiology & neurobiology · 2008Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During the last 20 to 30 years, numerous examples have been provided of neurons and endocrine cells that are able to produce, store, and in many cases release more than one type of signal molecule. Recent models propose that neurons often employ an amino acid, an amine, and one or more neuroactive peptides, and that endocrine cells may release more than one peptide hormone. In neurons, the different classes of transmitter convey fast, intermediate, and slow signalling respectively. However, a series of studies demonstrates that neurons may colocalize more than one neuroactive amino acid, and that endocrine cells may contain an amino acid along with their peptide hormone. These forms of colocalization seem to add new levels of complexity to the role of amino acids in cell signalling, suggesting that, in neurons, amino acids may interact at the receptor level, modifying the effect of each other, and that, in endocrine cells, amino acids may act together with or parallel to a peptide hormone in a paracrine or autocrine manner.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.