Evidence map›Paper›PMID 8796338›Full record

ArticleJournal of endocrinological investigation1996

Histamine receptors and bioeffects on clonal parathyroid endothelial cells.

U Frediani, S Benvenuti, L Masi, A L Tanini, M L Brandi

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of endocrinological investigation, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

U FredianiDipartimento di Fisiopatologia Clinica e, University of Firenze, Italy.
S Benvenuti
L Masi
A L Tanini
M L Brandi
University of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Using a clonal line of bovine parathyroid endothelial cells (BPE-1) we defined the presence on these cells of a histamine H2 receptor and characterized its pharmacological properties. Interaction of histamine with its receptor induced an increase of cAMP accumulation in a dose- and time-dependent fashion. This effect appears unique for parathyroid endothelial cells, in fact, clonal parathyroid epithelial cells did not exhibit a similar response. No effect of histamine was observed on BPE-1 cell proliferation.

Indexed as

AnimalsCattleCell LineCell MembraneCyclic AMPDimapritDNAEndotheliumHistamineHistamine H1 AntagonistsHistamine H2 AntagonistsIodine RadioisotopesKineticsParathyroid GlandsReceptors, Histamine H2APTCyclic AMPDimapritDNAHistamineHistamine H1 AntagonistsHistamine H2 AntagonistsIodine RadioisotopesReceptors, Histamine H2

Identifiers

PMID8796338
OpenAlexW2032493153

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.